Hs01995002_cn

• Gene Symbol: PPP1R16A
• Assay Reference Genome Location: Chr.8:144496817 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 84988
• Gene Name: protein phosphatase 1 regulatory subunit 16A
• Gene Aliases: MYPT3
• Location: Chr.8:144477987-144502121 on Build GRCh38
• Assay Gene Location: Within Exon 5

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP1R16A	XM_005272350.2	3	677	XP_005272407.1
	XM_017013912.1	4	746	XP_016869401.1
	XM_017013913.1	3	710	XP_016869402.1
	XM_017013914.1	4	784	XP_016869403.1
	XM_017013915.1	3	741	XP_016869404.1
	AK090471.1	3	607	BAC03452.1
	BC049841.1			AAH49841.1
	BC053506.1	1	92	AAH53506.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	LOC101928902 CPSF1 EXOSC4 SMPD5 MIR939 GRINA CYHR1 SLC39A4 KIFC2 SCX MROH1 MIR6847 GPT HSF1 RECQL4 MIR6849 CYC1 SLC52A2 SCRT1 MIR1234 LOC101928953 PLEC ADCK5 WDR97 TONSL-AS1 MAF1 LRRC14 TMEM249 HGH1 GPAA1 OPLAH MIR661 TONSL DGAT1 BOP1 PARP10 MIR6848 SPATC1 FBXL6 VPS28 MIR6846 MIR6893 FOXH1 PPP1R16A SHARPIN MFSD3 MIR7112
nsv612951	Chr.8:144479830 - 144677692 on Build GRCh38	Loss	GPT ARHGAP39 LRRC24 RECQL4 PPP1R16A LRRC14 MFSD3 C8orf82 LOC101928953
nsv831489	Chr.8:144342140 - 144544026 on Build GRCh38	Loss	LOC101928902 CPSF1 ARHGAP39 LRRC24 MIR939 CYHR1 SLC39A4 KIFC2 GPT RECQL4 MIR6849 SLC52A2 C8orf82 MIR1234 LOC101928953 ADCK5 TONSL-AS1 LRRC14 TMEM249 TONSL FBXL6 VPS28 MIR6893 FOXH1 PPP1R16A MFSD3
dgv12439n54	Chr.8:144438306 - 144525122 on Build GRCh38	Loss	GPT TONSL LRRC24 RECQL4 TONSL-AS1 FOXH1 PPP1R16A CYHR1 LRRC14 MFSD3 KIFC2 LOC101928953
nsv612955	Chr.8:144494912 - 144502322 on Build GRCh38	Loss	GPT PPP1R16A LOC101928953
nsv482126	Chr.8:144496726 - 144502120 on Build GRCh38	Gain	PPP1R16A LOC101928953
dgv907n27	Chr.8:144416180 - 144525122 on Build GRCh38	Loss	LRRC24 TONSL-AS1 CYHR1 LRRC14 SLC39A4 KIFC2 GPT TONSL RECQL4 VPS28 MIR6893 FOXH1 PPP1R16A MFSD3 LOC101928953
dgv12434n54	Chr.8:144270080 - 144516801 on Build GRCh38	Loss	LOC101928902 CPSF1 MIR939 CYHR1 SLC39A4 KIFC2 GPT HSF1 RECQL4 MIR6849 SLC52A2 SCRT1 MIR1234 LOC101928953 ADCK5 TONSL-AS1 TMEM249 TONSL DGAT1 BOP1 MIR6848 FBXL6 VPS28 MIR6893 FOXH1 PPP1R16A MFSD3
dgv12442n54	Chr.8:144492696 - 144516381 on Build GRCh38	Loss	GPT RECQL4 PPP1R16A MFSD3 LOC101928953
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	LOC101928902 CPSF1 EXOSC4 SMPD5 MIR939 GRINA CYHR1 SLC39A4 KIFC2 SCX MROH1 MIR6847 GPT HSF1 RECQL4 MIR6849 CYC1 SLC52A2 SCRT1 MIR1234 LOC101928953 PLEC ADCK5 WDR97 TONSL-AS1 MAF1 LRRC14 TMEM249 HGH1 GPAA1 OPLAH MIR661 TONSL DGAT1 BOP1 PARP10 MIR6848 SPATC1 FBXL6 VPS28 MIR6846 MIR6893 FOXH1 PPP1R16A SHARPIN MFSD3 MIR7112
nsv612940	Chr.8:144436292 - 144613673 on Build GRCh38	Loss	ARHGAP39 LRRC24 TONSL-AS1 CYHR1 LRRC14 KIFC2 GPT TONSL RECQL4 FOXH1 PPP1R16A MFSD3 C8orf82 LOC101928953
nsv428208	Chr.8:144041826 - 144722291 on Build GRCh38	Gain	LOC101928902 CPSF1 EXOSC4 ARHGAP39 LRRC24 SMPD5 MIR939 CYHR1 SLC39A4 KIFC2 ZNF251 SCX MROH1 MIR6847 GPT HSF1 RECQL4 MIR6849 CYC1 SLC52A2 C8orf82 SCRT1 MIR1234 LOC101928953 ADCK5 WDR97 TONSL-AS1 MAF1 LRRC14 TMEM249 HGH1 GPAA1 OPLAH TONSL DGAT1 BOP1 MIR6848 SPATC1 FBXL6 VPS28 MIR6846 MIR6893 FOXH1 PPP1R16A SHARPIN MFSD3 MIR7112
esv29999	Chr.8:144456732 - 144525122 on Build GRCh38	Loss	GPT LRRC24 RECQL4 FOXH1 PPP1R16A CYHR1 LRRC14 MFSD3 KIFC2 LOC101928953

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphatase modulator

Gene Ontology Categories:

Process(es)

regulation of catalytic activity

Function(s)

protein binding
protein phosphatase type 1 regulator activity