Hs01997433_cn

• Gene Symbol: TRMT2A
• Assay Reference Genome Location: Chr.22:20112182 on build GRCh38
• Cytoband: 22q11.21

Target Gene Details

• Entrez Gene ID: 27037
• Gene Name: tRNA methyltransferase 2 homolog A
• Gene Aliases: HTF9C
• Location: Chr.22:20111866-20117305 on Build GRCh38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRMT2A	NM_001257994.1	12	2670	NP_001244923.1
	NM_022727.5	12	2648	NP_073564.3
	NM_182984.4	13	2524	NP_892029.2
	XM_011530139.2	13	2509	XP_011528441.1
	XM_011530141.1	11	1884	XP_011528443.1
	XM_011530142.2	9	1542	XP_011528444.1
	XM_017028770.1	12	2712	XP_016884259.1
	AI539558.1	1	320
	BC017184.2	13	2410	AAH17184.2
	BX349507.2	1	279
	CA440188.1	1	334

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv726n67	Chr.22:20070444 - 20324465 on Build GRCh38	Gain	RANBP1 LINC00896 LOC440792 DGCR8 CCDC188 RTN4R MIR1306 MIR6816 ZDHHC8 MIR3618 LOC284865 DGCR6L MIR1286 TRMT2A
esv3893434	Chr.22:19470889 - 20343372 on Build GRCh38	Gain	C22orf29 LOC440792 MIR4761 RTN4R MIR1306 MIR6816 ZDHHC8 LOC284865 MIR1286 RANBP1 LINC00896 ARVCF DGCR8 UFD1L GP1BB CLDN5 CCDC188 TBX1 MIR3618 SEPT5-GP1BB LOC101927859 LINC00895 CDC45 TXNRD2 GNB1L TANGO2 DGCR6L SEPT5 COMT TRMT2A MIR185
esv3647284	Chr.22:19985583 - 20137122 on Build GRCh38	Gain	RANBP1 TANGO2 ARVCF DGCR8 TRMT2A MIR1306 MIR6816 ZDHHC8 MIR3618 MIR185
nsv828938	Chr.22:19691069 - 20324465 on Build GRCh38	Gain	C22orf29 LOC440792 MIR4761 RTN4R MIR1306 MIR6816 ZDHHC8 LOC284865 MIR1286 RANBP1 LINC00896 ARVCF DGCR8 GP1BB CCDC188 TBX1 MIR3618 SEPT5-GP1BB TXNRD2 GNB1L TANGO2 DGCR6L SEPT5 COMT TRMT2A MIR185
nsv828939	Chr.22:19696032 - 20324465 on Build GRCh38	Loss	C22orf29 LOC440792 MIR4761 RTN4R MIR1306 MIR6816 ZDHHC8 LOC284865 MIR1286 RANBP1 LINC00896 ARVCF DGCR8 GP1BB CCDC188 TBX1 MIR3618 SEPT5-GP1BB TXNRD2 GNB1L TANGO2 DGCR6L SEPT5 COMT TRMT2A MIR185
esv2758825	Chr.22:20038970 - 20321924 on Build GRCh38	Loss	RANBP1 LINC00896 LOC440792 DGCR8 CCDC188 RTN4R MIR1306 MIR6816 ZDHHC8 MIR3618 LOC284865 TANGO2 DGCR6L MIR1286 TRMT2A
dgv4480n100	Chr.22:20069620 - 20262667 on Build GRCh38	Gain	RANBP1 LOC284865 LINC00896 DGCR8 MIR1286 CCDC188 TRMT2A RTN4R MIR1306 MIR6816 ZDHHC8 MIR3618
nsv471183	Chr.22:20018517 - 20319470 on Build GRCh38	Loss	RANBP1 LINC00896 LOC440792 DGCR8 CCDC188 RTN4R MIR1306 MIR6816 ZDHHC8 MIR3618 LOC284865 TANGO2 DGCR6L MIR1286 TRMT2A MIR185
dgv7983n54	Chr.22:19762002 - 20321870 on Build GRCh38	Gain	RANBP1 C22orf29 LINC00896 LOC440792 ARVCF DGCR8 MIR4761 CCDC188 RTN4R MIR1306 MIR6816 TBX1 ZDHHC8 MIR3618 TXNRD2 GNB1L LOC284865 TANGO2 DGCR6L MIR1286 COMT TRMT2A MIR185
nsv834133	Chr.22:20029363 - 20176708 on Build GRCh38	Loss	RANBP1 TANGO2 DGCR8 CCDC188 TRMT2A MIR1306 MIR6816 ZDHHC8 MIR3618 MIR185
nsv953027	Chr.22:20085378 - 20303977 on Build GRCh38	Deletion	RANBP1 LINC00896 LOC440792 DGCR8 CCDC188 RTN4R MIR1306 MIR6816 ZDHHC8 MIR3618 LOC284865 MIR1286 TRMT2A

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA methyltransferase

Gene Ontology Categories:

Process(es)

RNA methylation
RNA processing

Function(s)

nucleotide binding
RNA methyltransferase activity
poly(A) RNA binding