Hs02008143_cn

• Gene Symbol: TRMT2A
• Assay Reference Genome Location: Chr.22:20112025 on build GRCh38
• Cytoband: 22q11.21

Target Gene Details

• Entrez Gene ID: 27037
• Gene Name: tRNA methyltransferase 2 homolog A
• Gene Aliases: HTF9C
• Location: Chr.22:20111866-20117305 on Build GRCh38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRMT2A	NM_001257994.1	12	2827	NP_001244923.1
	NM_022727.5	12	2805	NP_073564.3
	NM_182984.4	13	2681	NP_892029.2
	XM_011530139.2	13	2666	XP_011528441.1
	XM_011530141.1	11	2041	XP_011528443.1
	XM_011530142.2	9	1699	XP_011528444.1
	XM_017028770.1	12	2869	XP_016884259.1
	AI539558.1	1	163
	BC017184.2	13	2567	AAH17184.2
	BX349507.2	1	122
	CA440188.1	1	177

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv726n67	Chr.22:20070444 - 20324465 on Build GRCh38	Gain	DGCR6L DGCR8 ZDHHC8 MIR3618 LOC440792 RTN4R LOC284865 TRMT2A MIR1286 RANBP1 CCDC188 LINC00896 MIR1306 MIR6816
esv3893434	Chr.22:19470889 - 20343372 on Build GRCh38	Gain	DGCR6L DGCR8 ARVCF MIR3618 LOC440792 SEPT5-GP1BB LOC101927859 SEPT5 CLDN5 LINC00895 MIR4761 TBX1 MIR6816 GP1BB C22orf29 GNB1L ZDHHC8 TANGO2 UFD1L CDC45 COMT RTN4R LOC284865 TXNRD2 TRMT2A MIR1286 RANBP1 CCDC188 LINC00896 MIR185 MIR1306
esv3647284	Chr.22:19985583 - 20137122 on Build GRCh38	Gain	DGCR8 ARVCF TRMT2A RANBP1 ZDHHC8 TANGO2 MIR3618 MIR185 MIR1306 MIR6816
nsv828938	Chr.22:19691069 - 20324465 on Build GRCh38	Gain	DGCR6L DGCR8 ARVCF MIR3618 LOC440792 SEPT5-GP1BB SEPT5 MIR4761 TBX1 MIR6816 GP1BB C22orf29 GNB1L ZDHHC8 TANGO2 COMT RTN4R LOC284865 TXNRD2 TRMT2A MIR1286 RANBP1 CCDC188 LINC00896 MIR185 MIR1306
nsv828939	Chr.22:19696032 - 20324465 on Build GRCh38	Loss	DGCR6L DGCR8 ARVCF MIR3618 LOC440792 SEPT5-GP1BB SEPT5 MIR4761 TBX1 MIR6816 GP1BB C22orf29 GNB1L ZDHHC8 TANGO2 COMT RTN4R LOC284865 TXNRD2 TRMT2A MIR1286 RANBP1 CCDC188 LINC00896 MIR185 MIR1306
esv2758825	Chr.22:20038970 - 20321924 on Build GRCh38	Loss	DGCR6L DGCR8 ZDHHC8 TANGO2 MIR3618 LOC440792 RTN4R LOC284865 TRMT2A MIR1286 RANBP1 CCDC188 LINC00896 MIR1306 MIR6816
dgv4480n100	Chr.22:20069620 - 20262667 on Build GRCh38	Gain	DGCR8 RTN4R LOC284865 TRMT2A MIR1286 RANBP1 ZDHHC8 CCDC188 MIR3618 LINC00896 MIR1306 MIR6816
nsv471183	Chr.22:20018517 - 20319470 on Build GRCh38	Loss	DGCR6L DGCR8 ZDHHC8 TANGO2 MIR3618 LOC440792 RTN4R LOC284865 TRMT2A MIR1286 RANBP1 CCDC188 LINC00896 MIR185 MIR1306 MIR6816
dgv7983n54	Chr.22:19762002 - 20321870 on Build GRCh38	Gain	DGCR6L DGCR8 C22orf29 ARVCF GNB1L ZDHHC8 TANGO2 MIR3618 LOC440792 COMT RTN4R LOC284865 TXNRD2 TRMT2A MIR1286 RANBP1 CCDC188 MIR4761 TBX1 LINC00896 MIR185 MIR1306 MIR6816
nsv834133	Chr.22:20029363 - 20176708 on Build GRCh38	Loss	DGCR8 TRMT2A RANBP1 ZDHHC8 CCDC188 TANGO2 MIR3618 MIR185 MIR1306 MIR6816
nsv953027	Chr.22:20085378 - 20303977 on Build GRCh38	Deletion	DGCR8 ZDHHC8 MIR3618 LOC440792 RTN4R LOC284865 TRMT2A MIR1286 RANBP1 CCDC188 LINC00896 MIR1306 MIR6816

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA methyltransferase

Gene Ontology Categories:

Process(es)

RNA methylation
RNA processing

Function(s)

nucleotide binding
RNA methyltransferase activity
poly(A) RNA binding