Hs02066584_cn

• Gene Symbol: CNOT3
• Assay Reference Genome Location: Chr.19:54149717 on build GRCh38
• Cytoband: 19q13.42

Target Gene Details

• Entrez Gene ID: 4849
• Gene Name: CCR4-NOT transcription complex subunit 3
• Gene Aliases: LENG2, NOT3, NOT3H
• Location: Chr.19:54137689-54155708 on Build GRCh38
• Assay Gene Location: Overlaps Exon 13 - Intron 13

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CNOT3	NM_014516.3			NP_055331.1
	XM_005278279.1			XP_005278336.1
	XM_005278280.2			XP_005278337.1
	XM_005278281.1			XP_005278338.1
	XM_005278282.2			XP_005278339.1
	XM_011526992.1			XP_011525294.1
	XM_011526993.2			XP_011525295.1
	AB014591.1
	AF180474.1			AAF29828.1
	AK160386.1			BAD18729.1
	AK300434.1
	AL133647.1			CAB63766.1
	BC016474.1			AAH16474.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3644782	Chr.19:54138064 - 54154026 on Build GRCh38	Gain	CNOT3
nsv515623	Chr.19:54102901 - 54179150 on Build GRCh38	Loss	PRPF31 CNOT3 MBOAT7 NDUFA3 TMC4 LENG1 TFPT
nsv953613	Chr.19:54097214 - 54198733 on Build GRCh38	Deletion	TSEN34 PRPF31 CNOT3 OSCAR MBOAT7 NDUFA3 TMC4 LENG1 TFPT
esv2718812	Chr.19:53184636 - 54322450 on Build GRCh38	Deletion	MIR521-2 MIR518B MIR519D BIRC8 DPRX LILRA5 MIR516A1 MIR519A1 MIR526B MIR517B MIR518E MIR519C PRPF31 MIR516B1 MIR4752 MIR522 CNOT3 MIR371B MYADM TARM1 MBOAT7 LILRA6 MIR524 MIR1323 PRKCG MIR520F ZNF331 VN1R4 MIR515-1 MIR373 OSCAR MIR520H ZNF677 MIR526A2 MIR517C CACNG6 MIR520C CACNG8 MIR515-2 MIR512-2 MIR512-1 MIR516B2 MIR371A MIR526A1 MIR520E VSTM1 MIR527 TMC4 CACNG7 ZNF813 FAM90A27P TPM3P9 ZNF665 LILRB5 TSEN34 MIR935 MIR520G ZNF845 MIR520D ZNF765 MIR523 MIR372 LILRB3 MIR518A1 RPS9 MIR517A TFPT LILRB2 MIR498 MIR1283-2 MIR519A2 MIR518D MIR520B MIR519E ZNF818P LENG1 MIR520A ZNF761 MIR518C MIR1283-1 NDUFA3 MIR525 LOC105372457 NLRP12 MIR521-1 MIR516A2 ZNF525 LOC284379 VN1R2 MIR518A2 MIR518F MIR519B

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

general transcription factor

Gene Ontology Categories:

Process(es)

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
nuclear-transcribed mRNA poly(A) tail shortening
trophectodermal cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
negative regulation of translation
gene silencing by RNA
regulation of stem cell population maintenance

Function(s)

protein binding