Hs02091816_cn

• Gene Symbol: PTPN18
• Assay Reference Genome Location: Chr.2:130369187 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 26469
• Gene Name: protein tyrosine phosphatase, non-receptor type 18
• Gene Aliases: BDP1, PTP-HSCF
• Location: Chr.2:130356007-130375409 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTPN18	NM_001142370.1			NP_001135842.1
	NM_014369.3			NP_055184.2
	XM_006712416.3			XP_006712479.1
	XM_006712417.1			XP_006712480.1
	XM_017003798.1			XP_016859287.1
	AK303804.1
	BC024280.1			AAH24280.1
	BC041562.1			AAH41562.1
	BC052800.1			AAH52800.1
	BI261717.1
	X79568.1			CAA56105.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv998333	Chr.2:130059754 - 130454126 on Build GRCh38	Gain+Loss	CCDC74B MZT2B CCDC115 SMPD4 CYP4F62P TUBA3E PTPN18 MED15P9 FAR2P2 NOC2LP1 POTEF IMP4
nsv459341	Chr.2:130281566 - 130390535 on Build GRCh38	Loss	CCDC115 PTPN18 IMP4
esv2760631	Chr.2:130005319 - 130400286 on Build GRCh38	Gain+Loss	CCDC74B MZT2B CCDC115 SMPD4 TUBA3E PTPN18 MED15P9 FAR2P1 NOC2LP1 POTEF IMP4
dgv7079n54	Chr.2:130181715 - 130391244 on Build GRCh38	Loss	MZT2B CCDC115 SMPD4 TUBA3E PTPN18 NOC2LP1 IMP4
nsv583113	Chr.2:130132813 - 130369588 on Build GRCh38	Gain	CCDC74B MZT2B CCDC115 SMPD4 TUBA3E PTPN18 MED15P9 NOC2LP1 IMP4
esv3584065	Chr.2:130046530 - 130400286 on Build GRCh38	Loss	CCDC74B MZT2B CCDC115 SMPD4 TUBA3E PTPN18 MED15P9 FAR2P1 NOC2LP1 POTEF IMP4
nsv520559	Chr.2:130133334 - 130390535 on Build GRCh38	Gain+Loss	CCDC74B MZT2B CCDC115 SMPD4 TUBA3E PTPN18 MED15P9 NOC2LP1 IMP4
nsv1005664	Chr.2:130159287 - 130649604 on Build GRCh38	Loss	CFC1 CCDC115 SMPD4 TUBA3E TISP43 POTEI IMP4 MZT2B CYP4F62P POTEJ LOC646743 PTPN18 LOC107985778 FAR2P2 CFC1B NOC2LP1
esv2763387	Chr.2:130026123 - 130400286 on Build GRCh38	Loss	CCDC74B MZT2B CCDC115 SMPD4 TUBA3E PTPN18 MED15P9 FAR2P1 NOC2LP1 POTEF IMP4
dgv475n27	Chr.2:130185940 - 130390535 on Build GRCh38	Gain	MZT2B CCDC115 TUBA3E PTPN18 NOC2LP1 IMP4
dgv7083n54	Chr.2:130236250 - 130440530 on Build GRCh38	Loss	CCDC115 CYP4F62P PTPN18 FAR2P2 IMP4
nsv583046	Chr.2:128746961 - 130390535 on Build GRCh38	Loss	CCDC115 SMPD4 TUBA3E LOC151121 FAR2P1 RAB6C-AS1 IMP4 LOC101927881 CCDC74B MZT2B LOC101927924 LOC389033 PTPN18 MED15P9 RAB6C NOC2LP1 POTEF
esv3592450	Chr.2:130282861 - 130401532 on Build GRCh38	Loss	CCDC115 PTPN18 IMP4
nsv583132	Chr.2:130255764 - 130390535 on Build GRCh38	Gain	CCDC115 PTPN18 IMP4
nsv1001073	Chr.2:130290533 - 130400286 on Build GRCh38	Gain	CCDC115 PTPN18 IMP4
esv2751826	Chr.2:129606158 - 130385563 on Build GRCh38	Gain	CCDC115 SMPD4 TUBA3E FAR2P1 RAB6C-AS1 IMP4 CCDC74B MZT2B LOC101927924 LOC389033 PTPN18 MED15P9 RAB6C NOC2LP1 POTEF
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	CFC1 CCDC115 MZT2A FAR2P1 IMP4 MIR663B LOC646743 PTPN18 AMER3 MED15P9 PLEKHB2 POTEF ANKRD30BL TUBA3D TISP43 POTEI CCDC74A GPR39 FAM201B CCDC74B POTEJ FAR2P2 RAB6C LOC100507460 WTH3DI CYP4F30P SMPD4 TUBA3E MIR4784 C2orf27A LOC150776 LOC389033 CFC1B ZNF806 LINC01120 RAB6C-AS1 C2orf27B FAM168B ARHGEF4 MZT2B LINC01087 LOC101927924 POTEKP POTEE CYP4F62P LOC107985778 NOC2LP2 GPR148 NOC2LP1 LOC440910
dgv4073n100	Chr.2:130091652 - 130400286 on Build GRCh38	Gain	CCDC74B MZT2B CCDC115 SMPD4 TUBA3E PTPN18 MED15P9 NOC2LP1 POTEF IMP4
esv3893326	Chr.2:130080351 - 130492798 on Build GRCh38	Gain	CCDC115 SMPD4 TUBA3E POTEI IMP4 CCDC74B MZT2B CYP4F62P PTPN18 MED15P9 FAR2P2 NOC2LP1 POTEF
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	CFC1 CYP4F30P CCDC115 SMPD4 TUBA3E FAR2P1 IMP4 LOC389033 LOC646743 PTPN18 AMER3 MED15P9 CFC1B POTEF TISP43 POTEI RAB6C-AS1 ARHGEF4 CCDC74B MZT2B LOC101927924 CYP4F62P POTEJ LOC107985778 GPR148 FAR2P2 RAB6C NOC2LP1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein dephosphorylation
peptidyl-tyrosine dephosphorylation

Function(s)

non-membrane spanning protein tyrosine phosphatase activity
protein binding