Hs02096481_cn

• Gene Symbol: TKFC
• Assay Reference Genome Location: Chr.11:61348327 on build GRCh38
• Cytoband: 11q12.2

Target Gene Details

• Entrez Gene ID: 26007
• Gene Name: triokinase and FMN cyclase
• Gene Aliases: DAK, NET45
• Location: Chr.11:61333182-61353426 on Build GRCh38
• Assay Gene Location: Within Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TKFC	NM_015533.3	18	3809	NP_056348.2
	XM_011544912.2	18	3353	XP_011543214.1
	XM_017017517.1	18	5027	XP_016873006.1
	XM_017017518.1			XP_016873007.1
	XM_017017519.1	17	2265	XP_016873008.1
	XM_017017522.1			XP_016873011.1
	AK094516.1	1	1213

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428259	Chr.11:61049513 - 61356164 on Build GRCh38	Gain+Loss	PGA3 PGA5 VPS37C VWCE TKFC CD5 LOC105369325 PGA4 DDB1 CYB561A3
nsv832177	Chr.11:61185118 - 61356164 on Build GRCh38	Loss	PGA3 PGA5 VWCE TKFC PGA4 DDB1 CYB561A3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

cyclase

Gene Ontology Categories:

Process(es)

glycerol metabolic process
negative regulation of MDA-5 signaling pathway
cellular carbohydrate metabolic process
innate immune response
regulation of innate immune response
carbohydrate phosphorylation
fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

Function(s)

glycerone kinase activity
protein binding
ATP binding
FAD-AMP lyase (cyclizing) activity
metal ion binding
triokinase activity