Hs02106988_cn

• Gene Symbol: SLA
• Assay Reference Genome Location: Chr.8:133047914 on build GRCh38
• Cytoband: 8q24.22

Target Gene Details

• Entrez Gene ID: 6503
• Gene Name: Src-like-adaptor
• Gene Aliases: SLA1, SLAP
• Location: Chr.8:133036728-133103360 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SLA	NM_001045556.2			NP_001039021.1
	NM_001045557.2			NP_001039022.2
	NM_001282964.1			NP_001269893.1
	NM_001282965.1			NP_001269894.1
	NM_006748.3			NP_006739.2
	XM_017013739.1			XP_016869228.1
	AK297423.1
	AK297519.1
	AK310092.1
	AK312584.1
	BC007042.1			AAH07042.1
	BT019994.1			AAV38797.1
	BX648382.1
	CR536537.1			CAG38774.1
	D89077.1			BAA13758.1
	DA999385.1
	DB265860.1
	U30473.1			AAC50357.1
	U44403.1			AAC27662.1

Target Gene Details

• Entrez Gene ID: 7038
• Gene Name: thyroglobulin
• Gene Aliases: AITD3, TGN
• Location: Chr.8:132866943-133134902 on Build GRCh38
• Assay Gene Location: Within Intron 44

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TG	NM_003235.4			NP_003226.4
	XM_005251038.4			XP_005251095.1
	XM_006716622.3			XP_006716685.1
	XM_017013793.1			XP_016869282.1
	XM_017013794.1			XP_016869283.1
	XM_017013795.1			XP_016869284.1
	XM_017013796.1			XP_016869285.1
	XM_017013797.1			XP_016869286.1
	XM_017013798.1			XP_016869287.1
	AB209159.1			BAD92396.1
	AK299197.1
	AK303666.1
	AK303667.1
	BC127887.1
	BC140933.1
	U93033.2			AAC51924.1
	X05615.1			CAA29104.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv482993	Chr.8:132994656 - 133137835 on Build GRCh38	Loss	MIR7848 TG SLA
nsv6402	Chr.8:133043596 - 133072827 on Build GRCh38	Insertion	MIR7848 TG SLA

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

kinase modulator, scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

positive regulation of signal transduction
thyroid hormone generation
signal transduction
response to pH
iodide transport
thyroid gland development
regulation of myelination
response to lipopolysaccharide
hormone biosynthetic process
transcytosis

Function(s)

SH3/SH2 adaptor activity
protein binding
hormone activity
protein complex binding
protein homodimerization activity
anion binding
chaperone binding
carboxylic ester hydrolase activity