Hs02121945_cn

• Gene Symbol: TRMT2A
• Assay Reference Genome Location: Chr.22:20112732 on build GRCh38
• Cytoband: 22q11.21

Target Gene Details

• Entrez Gene ID: 27037
• Gene Name: tRNA methyltransferase 2 homolog A
• Gene Aliases: HTF9C
• Location: Chr.22:20111866-20117305 on Build GRCh38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRMT2A	NM_001257994.1	12	2120	NP_001244923.1
	NM_022727.5	12	2098	NP_073564.3
	NM_182984.4	13	1974	NP_892029.2
	XM_011530139.2	13	1959	XP_011528441.1
	XM_011530141.1	11	1334	XP_011528443.1
	XM_011530142.2	9	992	XP_011528444.1
	XM_017028770.1	12	2162	XP_016884259.1
	AK025106.1	11	1494	BAB15067.1
	AK057029.1	12	2070	BAB71349.1
	BC013352.2	12	1743	AAH13352.2
	BC017184.2	13	1860	AAH17184.2
	BC108251.1	12	1778	AAI08252.1
	BX349507.2	1	829
	CR456354.1	12	1819	CAG30240.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv726n67	Chr.22:20070444 - 20324465 on Build GRCh38	Gain	DGCR8 RANBP1 LINC00896 MIR1306 MIR1286 LOC284865 MIR3618 TRMT2A LOC440792 RTN4R MIR6816 ZDHHC8 CCDC188 DGCR6L
esv3893434	Chr.22:19470889 - 20343372 on Build GRCh38	Gain	MIR3618 TRMT2A ARVCF LINC00895 LOC101927859 RTN4R COMT SEPT5 MIR6816 MIR185 TXNRD2 UFD1L DGCR8 RANBP1 TBX1 LINC00896 MIR1306 MIR1286 GNB1L LOC284865 C22orf29 SEPT5-GP1BB LOC440792 CLDN5 CDC45 MIR4761 ZDHHC8 GP1BB CCDC188 DGCR6L TANGO2
esv3647284	Chr.22:19985583 - 20137122 on Build GRCh38	Gain	DGCR8 RANBP1 MIR1306 MIR3618 MIR6816 MIR185 TRMT2A ARVCF ZDHHC8 TANGO2
nsv828938	Chr.22:19691069 - 20324465 on Build GRCh38	Gain	MIR3618 TRMT2A ARVCF RTN4R COMT SEPT5 MIR6816 MIR185 TXNRD2 DGCR8 RANBP1 TBX1 LINC00896 MIR1306 MIR1286 GNB1L LOC284865 C22orf29 SEPT5-GP1BB LOC440792 MIR4761 ZDHHC8 GP1BB CCDC188 DGCR6L TANGO2
nsv828939	Chr.22:19696032 - 20324465 on Build GRCh38	Loss	MIR3618 TRMT2A ARVCF RTN4R COMT SEPT5 MIR6816 MIR185 TXNRD2 DGCR8 RANBP1 TBX1 LINC00896 MIR1306 MIR1286 GNB1L LOC284865 C22orf29 SEPT5-GP1BB LOC440792 MIR4761 ZDHHC8 GP1BB CCDC188 DGCR6L TANGO2
esv2758825	Chr.22:20038970 - 20321924 on Build GRCh38	Loss	DGCR8 RANBP1 LINC00896 MIR1306 MIR1286 LOC284865 MIR3618 TRMT2A LOC440792 RTN4R MIR6816 ZDHHC8 CCDC188 DGCR6L TANGO2
dgv4480n100	Chr.22:20069620 - 20262667 on Build GRCh38	Gain	DGCR8 RANBP1 RTN4R LINC00896 MIR1306 MIR1286 LOC284865 MIR3618 MIR6816 TRMT2A ZDHHC8 CCDC188
nsv471183	Chr.22:20018517 - 20319470 on Build GRCh38	Loss	DGCR8 RANBP1 LINC00896 MIR1306 MIR1286 LOC284865 MIR3618 TRMT2A LOC440792 RTN4R MIR6816 MIR185 ZDHHC8 CCDC188 DGCR6L TANGO2
esv3647287	Chr.22:20112473 - 20112776 on Build GRCh38	Insertion	TRMT2A
dgv7983n54	Chr.22:19762002 - 20321870 on Build GRCh38	Gain	DGCR8 RANBP1 TBX1 LINC00896 MIR1306 MIR1286 GNB1L LOC284865 MIR3618 TRMT2A ARVCF C22orf29 LOC440792 RTN4R COMT MIR6816 MIR185 MIR4761 ZDHHC8 CCDC188 DGCR6L TXNRD2 TANGO2
nsv834133	Chr.22:20029363 - 20176708 on Build GRCh38	Loss	DGCR8 RANBP1 MIR1306 MIR3618 MIR6816 MIR185 TRMT2A ZDHHC8 CCDC188 TANGO2
nsv953027	Chr.22:20085378 - 20303977 on Build GRCh38	Deletion	DGCR8 RANBP1 LINC00896 MIR1306 MIR1286 LOC284865 MIR3618 TRMT2A LOC440792 RTN4R MIR6816 ZDHHC8 CCDC188

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA methyltransferase

Gene Ontology Categories:

Process(es)

RNA methylation
RNA processing

Function(s)

nucleotide binding
RNA methyltransferase activity
poly(A) RNA binding