Hs02121945_cn

• Gene Symbol: TRMT2A
• Assay Reference Genome Location: Chr.22:20112732 on build GRCh38
• Cytoband: 22q11.21

Target Gene Details

• Entrez Gene ID: 27037
• Gene Name: tRNA methyltransferase 2 homolog A
• Gene Aliases: HTF9C
• Location: Chr.22:20111866-20117305 on Build GRCh38
• Assay Gene Location: Within Exon 12

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TRMT2A	NM_001257994.1	12	2120	NP_001244923.1
	NM_022727.5	12	2098	NP_073564.3
	NM_182984.4	13	1974	NP_892029.2
	XM_011530139.2	13	1959	XP_011528441.1
	XM_011530141.1	11	1334	XP_011528443.1
	XM_011530142.2	9	992	XP_011528444.1
	XM_017028770.1	12	2162	XP_016884259.1
	AK025106.1	11	1494	BAB15067.1
	AK057029.1	12	2070	BAB71349.1
	BC013352.2	12	1743	AAH13352.2
	BC017184.2	13	1860	AAH17184.2
	BC108251.1	12	1778	AAI08252.1
	BX349507.2	1	829
	CR456354.1	12	1819	CAG30240.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv726n67	Chr.22:20070444 - 20324465 on Build GRCh38	Gain	RTN4R DGCR8 DGCR6L CCDC188 MIR3618 ZDHHC8 LOC440792 LOC284865 MIR1306 RANBP1 MIR6816 MIR1286 LINC00896 TRMT2A
esv3647284	Chr.22:19985583 - 20137122 on Build GRCh38	Gain	MIR1306 DGCR8 RANBP1 MIR6816 TANGO2 MIR185 ARVCF MIR3618 ZDHHC8 TRMT2A
esv3893434	Chr.22:19470889 - 20343372 on Build GRCh38	Gain	TBX1 COMT MIR185 DGCR6L TXNRD2 MIR3618 ZDHHC8 CLDN5 LOC440792 SEPT5 LINC00895 LOC284865 MIR6816 TANGO2 LINC00896 UFD1L SEPT5-GP1BB TRMT2A MIR4761 RTN4R LOC101927859 GP1BB DGCR8 CCDC188 CDC45 GNB1L C22orf29 MIR1306 RANBP1 MIR1286 ARVCF
esv2758825	Chr.22:20038970 - 20321924 on Build GRCh38	Loss	RTN4R DGCR8 DGCR6L CCDC188 MIR3618 ZDHHC8 LOC440792 LOC284865 MIR1306 RANBP1 MIR6816 MIR1286 TANGO2 LINC00896 TRMT2A
nsv828939	Chr.22:19696032 - 20324465 on Build GRCh38	Loss	TBX1 COMT MIR185 DGCR6L TXNRD2 MIR3618 ZDHHC8 LOC440792 SEPT5 LOC284865 MIR6816 TANGO2 LINC00896 SEPT5-GP1BB TRMT2A MIR4761 RTN4R GP1BB DGCR8 CCDC188 GNB1L C22orf29 MIR1306 RANBP1 MIR1286 ARVCF
nsv828938	Chr.22:19691069 - 20324465 on Build GRCh38	Gain	TBX1 COMT MIR185 DGCR6L TXNRD2 MIR3618 ZDHHC8 LOC440792 SEPT5 LOC284865 MIR6816 TANGO2 LINC00896 SEPT5-GP1BB TRMT2A MIR4761 RTN4R GP1BB DGCR8 CCDC188 GNB1L C22orf29 MIR1306 RANBP1 MIR1286 ARVCF
dgv4480n100	Chr.22:20069620 - 20262667 on Build GRCh38	Gain	RTN4R LOC284865 MIR1306 DGCR8 RANBP1 MIR6816 MIR1286 CCDC188 MIR3618 LINC00896 ZDHHC8 TRMT2A
nsv471183	Chr.22:20018517 - 20319470 on Build GRCh38	Loss	RTN4R DGCR8 MIR185 DGCR6L CCDC188 MIR3618 ZDHHC8 LOC440792 LOC284865 MIR1306 RANBP1 MIR6816 MIR1286 TANGO2 LINC00896 TRMT2A
esv3647287	Chr.22:20112473 - 20112776 on Build GRCh38	Insertion	TRMT2A
nsv953027	Chr.22:20085378 - 20303977 on Build GRCh38	Deletion	RTN4R DGCR8 CCDC188 MIR3618 ZDHHC8 LOC440792 LOC284865 MIR1306 RANBP1 MIR6816 MIR1286 LINC00896 TRMT2A
nsv834133	Chr.22:20029363 - 20176708 on Build GRCh38	Loss	MIR1306 DGCR8 RANBP1 MIR6816 TANGO2 MIR185 CCDC188 MIR3618 ZDHHC8 TRMT2A
dgv7983n54	Chr.22:19762002 - 20321870 on Build GRCh38	Gain	RTN4R TBX1 DGCR8 COMT MIR185 DGCR6L CCDC188 TXNRD2 MIR3618 GNB1L ZDHHC8 LOC440792 C22orf29 LOC284865 MIR1306 RANBP1 MIR6816 MIR1286 TANGO2 ARVCF LINC00896 TRMT2A MIR4761

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA methyltransferase

Gene Ontology Categories:

Process(es)

RNA methylation
RNA processing

Function(s)

nucleotide binding
RNA methyltransferase activity
poly(A) RNA binding