Hs02153202_cn

• Gene Symbol: STAT5B
• Assay Reference Genome Location: Chr.17:42199478 on build GRCh38
• Cytoband: 17q21.2

Target Gene Details

• Entrez Gene ID: 6777
• Gene Name: signal transducer and activator of transcription 5B
• Gene Aliases: STAT5
• Location: Chr.17:42199177-42276460 on Build GRCh38
• Assay Gene Location: Within Exon 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
STAT5B	NM_012448.3	19	4793	NP_036580.2
	XM_017024977.1	18	4612	XP_016880466.1
	AB208920.1	19	4772	BAD92157.1
	AL080218.1	1	1299
	BC065227.1	19	4793	AAH65227.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1056904	Chr.17:42025823 - 42363204 on Build GRCh38	Gain	KCNH4 RAB5C ZNF385C STAT5A HSPB9 GHDC HCRT STAT5B STAT3 DHX58 KAT2A

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-binding transcription factor

Gene Ontology Categories:

Process(es)

allantoin metabolic process
luteinization
response to hypoxia
natural killer cell differentiation
liver development
citrate metabolic process
2-oxoglutarate metabolic process
succinate metabolic process
oxaloacetate metabolic process
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
isoleucine metabolic process
valine metabolic process
creatine metabolic process
fatty acid metabolic process
acute-phase response
JAK-STAT cascade
female pregnancy
lactation
peptidyl-tyrosine phosphorylation
regulation of steroid metabolic process
taurine metabolic process
lipid storage
regulation of epithelial cell differentiation
response to estradiol
response to lipopolysaccharide
positive regulation of natural killer cell proliferation
positive regulation of natural killer cell differentiation
cellular response to hormone stimulus
T cell differentiation in thymus
prolactin signaling pathway
regulation of multicellular organism growth
positive regulation of multicellular organism growth
positive regulation of activated T cell proliferation
progesterone metabolic process
T cell homeostasis
negative regulation of apoptotic process
positive regulation of interleukin-2 biosynthetic process
response to ethanol
positive regulation of B cell differentiation
positive regulation of gamma-delta T cell differentiation
negative regulation of erythrocyte differentiation
positive regulation of erythrocyte differentiation
positive regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
positive regulation of natural killer cell mediated cytotoxicity
creatinine metabolic process
development of secondary female sexual characteristics
development of secondary male sexual characteristics
Peyer's patch development
positive regulation of smooth muscle cell proliferation
positive regulation of inflammatory response
positive regulation of cellular component movement
JAK-STAT cascade involved in growth hormone signaling pathway
response to interleukin-2
response to interleukin-4
response to interleukin-15
cellular response to growth factor stimulus
cellular response to epidermal growth factor stimulus
mast cell migration

Function(s)

RNA polymerase II core promoter sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein tyrosine kinase activity
signal transducer activity
protein binding
protein phosphatase binding
glucocorticoid receptor binding
protein dimerization activity