Hs02176211_cn

• Gene Symbol: PPP1R8
• Assay Reference Genome Location: Chr.1:27850777 on build GRCh38
• Cytoband: 1p35.3

Target Gene Details

• Entrez Gene ID: 5511
• Gene Name: protein phosphatase 1 regulatory subunit 8
• Gene Aliases: ARD-1, ARD1, NIPP-1, NIPP1, PRO2047
• Location: Chr.1:27830741-27851672 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP1R8	NM_002713.3	6	1663	NP_002704.1
	NM_014110.4	7	1482	NP_054829.2
	NM_138558.2	7	1764	NP_612568.1
	XM_017001594.1	6	1183	XP_016857083.1
	AF061958.1	7	1410	AAD31541.1
	AF061959.1	7	1565	AAD31542.1
	AF126488.1	7	1398	AAD22486.1
	AX775985.1	7	1398	CAE11692.1
	BC001597.1	6	1290	AAH01597.1
	BC013360.2	6	1340	AAH13360.1
	BC093017.1	7	1402	AAH93017.1
	DQ223931.1			ABB04281.1
	U14575.1	6	1650	AAA64749.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv509069	Chr.1:27817460 - 27905956 on Build GRCh38	Insertion	THEMIS2 RPA2 PPP1R8 STX12 SCARNA1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA splicing factor

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA processing
RNA catabolic process
cell proliferation
RNA splicing
negative regulation of catalytic activity
RNA phosphodiester bond hydrolysis

Function(s)

DNA binding
RNA binding
endonuclease activity
protein serine/threonine phosphatase inhibitor activity
protein binding
protein phosphatase type 1 regulator activity
ribonuclease E activity