Hs02216673_cn

• Gene Symbol: BLK
• Assay Reference Genome Location: Chr.8:11494297 on build GRCh38
• Cytoband: 8p23.1

Target Gene Details

• Entrez Gene ID: 640
• Gene Name: BLK proto-oncogene, Src family tyrosine kinase
• Gene Aliases: MODY11
• Location: Chr.8:11493991-11564599 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
BLK	NM_001715.2	1	286	NP_001706.2
	XM_011543824.1	1	307	XP_011542126.1
	XM_011543827.1	1	307	XP_011542129.1
	XM_011543828.2	1	307	XP_011542130.1
	XM_011543829.2	1	307	XP_011542131.1
	XM_017013730.1	1	307	XP_016869219.1
	BC018703.1	1	150
	BQ057058.1	1	286
	S76617.1	1	297	AAB33265.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv34097	Chr.8:11319863 - 11632385 on Build GRCh38	Loss	SLC35G5 FAM167A-AS1 LOC101929290 MTMR9 LINC00208 BLK TDH FAM167A

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

kinase modulator

Gene Ontology Categories:

Process(es)

cytoskeleton organization
transmembrane receptor protein tyrosine kinase signaling pathway
cell differentiation
positive regulation of insulin secretion
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
negative regulation of apoptotic process
innate immune response
regulation of phagocytosis
B cell receptor signaling pathway
regulation of podosome assembly

Function(s)

protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding