Hs02232555_cn

• Gene Symbol: CDT1
• Assay Reference Genome Location: Chr.16:88807296 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 81620
• Gene Name: chromatin licensing and DNA replication factor 1
• Gene Aliases: DUP, RIS2
• Location: Chr.16:88803778-88809258 on Build GRCh38
• Assay Gene Location: Overlaps Intron 8 - Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDT1	NM_030928.3			NP_112190.2
	AB053172.1			BAB61878.1
	AF070552.1
	AF321125.1			AAG45181.1
	BC000137.2			AAH00137.2
	BC008676.1			AAH08676.1
	BC008860.2			AAH08860.2
	BC009410.1			AAH09410.1
	BC014202.2			AAH14202.2
	BC021126.1
	BC049205.1			AAH49205.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	CDH15 LINC00304 PABPN1L ZNF778 GALNS APRT LOC107987238 CBFA2T3 TRAPPC2L CTU2 LOC105371409 MIR4722 SLC22A31 CDT1 LOC100129697 LOC400558 ACSF3 LOC101927793 PIEZO1 LOC339059 LOC100289580
nsv457617	Chr.16:88801844 - 88829729 on Build GRCh38	Gain	CDT1 GALNS APRT LOC107987238
dgv3064n100	Chr.16:88683753 - 88846491 on Build GRCh38	Gain	SNAI3-AS1 MIR4722 CDT1 GALNS APRT SNAI3 RNF166 LOC107987238 PIEZO1 LOC339059 CTU2 LOC100289580
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	CDH15 LOC100287036 LINC00304 PABPN1L ZNF778 LOC105371414 GALNS APRT LOC107987238 ANKRD11 CBFA2T3 TRAPPC2L LOC105371409 SLC22A31 CDT1 LOC100129697 LOC400558 ACSF3 LOC101927793 PIEZO1 LOC339059 LOC100289580
nsv952071	Chr.16:88790893 - 89019992 on Build GRCh38	Deletion	PABPN1L CDT1 GALNS APRT LOC100129697 LOC107987238 CBFA2T3 TRAPPC2L LOC101927793 LOC105371409
nsv521217	Chr.16:88805821 - 89174375 on Build GRCh38	Loss	CDH15 LINC00304 PABPN1L GALNS APRT LOC107987238 CBFA2T3 TRAPPC2L LOC105371409 CDT1 LOC100129697 LOC400558 ACSF3 LOC101927793
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	FANCA CDH15 GAS8 LOC100287036 IL17C LOC107984817 MC1R TRAPPC2L RPL13 TUBB8P7 MIR4722 AFG3L1P RNF166 LOC100129697 LOC400558 ACSF3 FAM157C SPATA2L CPNE7 CYBA LINC00304 SPG7 VPS9D1-AS1 CBFA2T3 TUBB3 SPATA33 LOC105371409 SNAI3-AS1 SLC22A31 SNORD68 LOC100289580 ZNF276 LOC105371414 GALNS VPS9D1 TCF25 ANKRD11 CENPBD1 CDT1 CHMP1A CDK10 LOC101927793 PIEZO1 PRDM7 GAS8-AS1 PABPN1L ZNF778 APRT LOC107987238 URAHP LOC105371419 CTU2 DEF8 LOC101927817 MVD SNAI3 DBNDD1 DPEP1 SPIRE2 LOC339059
nsv1063441	Chr.16:88767066 - 88861882 on Build GRCh38	Loss	CDT1 GALNS APRT LOC107987238 TRAPPC2L PIEZO1
dgv37n68	Chr.16:88767460 - 88944903 on Build GRCh38	Loss	PABPN1L CDT1 GALNS APRT LOC100129697 LOC107987238 CBFA2T3 TRAPPC2L LOC101927793 PIEZO1 LOC105371409
nsv573718	Chr.16:88807259 - 88810716 on Build GRCh38	Loss	CDT1 APRT
esv3639555	Chr.16:88745961 - 88899576 on Build GRCh38	Gain	PABPN1L CDT1 GALNS APRT LOC107987238 CBFA2T3 TRAPPC2L LOC101927793 PIEZO1
nsv573715	Chr.16:88804814 - 88808224 on Build GRCh38	Loss	CDT1
nsv1061256	Chr.16:88711587 - 89013365 on Build GRCh38	Gain	PABPN1L GALNS APRT LOC107987238 CBFA2T3 TRAPPC2L CTU2 LOC105371409 MIR4722 CDT1 LOC100129697 LOC101927793 PIEZO1 LOC339059 LOC100289580
nsv573712	Chr.16:88796728 - 88809084 on Build GRCh38	Loss	CDT1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

DNA replication checkpoint
G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
DNA replication
regulation of DNA-dependent DNA replication initiation
regulation of nuclear cell cycle DNA replication

Function(s)

DNA binding
protein binding