Hs02297964_cn

• Gene Symbol: CDT1
• Assay Reference Genome Location: Chr.16:88806071 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 81620
• Gene Name: chromatin licensing and DNA replication factor 1
• Gene Aliases: DUP, RIS2
• Location: Chr.16:88803778-88809258 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDT1	NM_030928.3			NP_112190.2
	AB053172.1			BAB61878.1
	AF070552.1
	AF321125.1			AAG45181.1
	BC000137.2			AAH00137.2
	BC008676.1			AAH08676.1
	BC008860.2			AAH08860.2
	BC009410.1			AAH09410.1
	BC014202.2			AAH14202.2
	BC021126.1
	BC049205.1			AAH49205.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv5313n54	Chr.16:88795879 - 88806103 on Build GRCh38	Loss	CDT1
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	CDH15 APRT PABPN1L LINC00304 CBFA2T3 LOC107987238 SLC22A31 ZNF778 LOC100129697 TRAPPC2L CDT1 GALNS PIEZO1 LOC100289580 MIR4722 LOC105371409 LOC400558 ACSF3 LOC339059 CTU2 LOC101927793
nsv457617	Chr.16:88801844 - 88829729 on Build GRCh38	Gain	APRT LOC107987238 CDT1 GALNS
dgv3064n100	Chr.16:88683753 - 88846491 on Build GRCh38	Gain	APRT SNAI3-AS1 LOC107987238 LOC339059 SNAI3 CDT1 RNF166 GALNS PIEZO1 CTU2 LOC100289580 MIR4722
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	CDH15 APRT LOC105371414 PABPN1L LINC00304 CBFA2T3 LOC107987238 SLC22A31 ZNF778 ANKRD11 LOC100129697 TRAPPC2L CDT1 GALNS PIEZO1 LOC100289580 LOC105371409 LOC400558 LOC100287036 ACSF3 LOC339059 LOC101927793
nsv952071	Chr.16:88790893 - 89019992 on Build GRCh38	Deletion	APRT PABPN1L CBFA2T3 LOC107987238 LOC100129697 TRAPPC2L CDT1 GALNS LOC105371409 LOC101927793
nsv521217	Chr.16:88805821 - 89174375 on Build GRCh38	Loss	CDH15 APRT PABPN1L LINC00304 CBFA2T3 LOC107987238 LOC100129697 TRAPPC2L CDT1 GALNS LOC105371409 LOC400558 ACSF3 LOC101927793
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	CHMP1A SPATA33 LOC105371414 ANKRD11 TUBB8P7 PIEZO1 LOC100289580 LOC107984817 VPS9D1 LOC105371419 DPEP1 CDH15 SNAI3-AS1 LOC107987238 SLC22A31 ZNF778 CDT1 FAM157C GALNS SPG7 FANCA LOC100287036 VPS9D1-AS1 AFG3L1P ACSF3 LOC339059 LOC101927817 GAS8 URAHP IL17C CBFA2T3 LOC100129697 CYBA RNF166 SNORD68 LOC105371409 MC1R DBNDD1 SPATA2L TUBB3 LOC101927793 APRT PABPN1L ZNF276 LINC00304 CDK10 TCF25 DEF8 TRAPPC2L CPNE7 MIR4722 MVD LOC400558 RPL13 SPIRE2 CENPBD1 GAS8-AS1 SNAI3 PRDM7 CTU2
nsv1063441	Chr.16:88767066 - 88861882 on Build GRCh38	Loss	APRT LOC107987238 TRAPPC2L CDT1 GALNS PIEZO1
dgv37n68	Chr.16:88767460 - 88944903 on Build GRCh38	Loss	APRT PABPN1L CBFA2T3 LOC107987238 LOC100129697 TRAPPC2L CDT1 GALNS PIEZO1 LOC105371409 LOC101927793
esv3639555	Chr.16:88745961 - 88899576 on Build GRCh38	Gain	APRT PABPN1L CBFA2T3 LOC107987238 TRAPPC2L CDT1 GALNS PIEZO1 LOC101927793
nsv573715	Chr.16:88804814 - 88808224 on Build GRCh38	Loss	CDT1
nsv1061256	Chr.16:88711587 - 89013365 on Build GRCh38	Gain	APRT PABPN1L CBFA2T3 LOC107987238 LOC100129697 TRAPPC2L CDT1 GALNS PIEZO1 LOC100289580 MIR4722 LOC105371409 LOC339059 CTU2 LOC101927793
nsv573712	Chr.16:88796728 - 88809084 on Build GRCh38	Loss	CDT1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

DNA replication checkpoint
G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
DNA replication
regulation of DNA-dependent DNA replication initiation
regulation of nuclear cell cycle DNA replication

Function(s)

DNA binding
protein binding