Hs02391968_cn

• Gene Symbol: MECOM
• Assay Reference Genome Location: Chr.3:169092966 on build GRCh38
• Cytoband: 3q26.2

Target Gene Details

• Entrez Gene ID: 2122
• Gene Name: MDS1 and EVI1 complex locus
• Gene Aliases: AML1-EVI-1, EVI1, MDS1, MDS1-EVI1, PRDM3, RUSAT2
• Location: Chr.3:169083499-169663781 on Build GRCh38
• Assay Gene Location: Overlaps Intron 18 - Exon 18

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MECOM	NM_001105077.3			NP_001098547.3
	NM_001105078.3			NP_001098548.2
	NM_001163999.1			NP_001157471.1
	NM_001164000.1			NP_001157472.1
	NM_001205194.1			NP_001192123.1
	NM_004991.3			NP_004982.2
	NM_005241.3			NP_005232.2
	XM_005247213.3			XP_005247270.1
	XM_005247214.3			XP_005247271.1
	XM_005247215.3			XP_005247272.1
	XM_005247219.2			XP_005247276.1
	XM_005247220.2			XP_005247277.1
	XM_005247221.2			XP_005247278.1
	XM_005247223.2			XP_005247280.1
	XM_005247224.3			XP_005247281.1
	XM_005247225.3			XP_005247282.1
	XM_005247226.3			XP_005247283.1
	XM_011512546.2			XP_011510848.1
	XM_017005874.1			XP_016861363.1
	XM_017005875.1			XP_016861364.1
	XM_017005876.1			XP_016861365.1
	XM_017005877.1			XP_016861366.1
	XM_017005878.1			XP_016861367.1
	AK025934.1
	AK292865.1
	AK304098.1
	AK310509.1
	BC031019.1			AAH31019.1
	BC130520.1
	BC143951.1
	BC143952.1
	BX640908.1			CAE45952.1
	BX647613.1			CAI46086.1
	GQ352634.1
	X54989.1			CAA38735.1

More Information

Additional Information:

For this assay, SNP(s) [rs147010550] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Non-exonic, non-DGV Variation

Panther Classification:

Molecular Function -

C2H2 zinc finger transcription factor

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
apoptotic process
cell differentiation
histone lysine methylation
negative regulation of programmed cell death
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
negative regulation of JNK cascade
regulation of cell cycle
hematopoietic stem cell proliferation

Function(s)

DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
histone-lysine N-methyltransferase activity
metal ion binding