Hs02429433_cn

• Gene Symbol: RNASE3
• Assay Reference Genome Location: Chr.14:20891997 on build GRCh38
• Cytoband: 14q11.2

Target Gene Details

• Entrez Gene ID: 6037
• Gene Name: ribonuclease A family member 3
• Gene Aliases: ECP, RAF1, RNS3
• Location: Chr.14:20891403-20892348 on Build GRCh38
• Assay Gene Location: Within Exon 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RNASE3	NM_002935.2	2	365	NP_002926.2
	BC096060.1	2	353	AAH96060.1
	BC096061.3	2	350	AAH96061.1
	BC096062.3	2	350	AAH96062.1
	BX280390.1	2	362
	M28128.1	2	363	AAA50283.1
	X15161.1	2	365	CAA33251.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv34e203	Chr.14:20877548 - 20957189 on Build GRCh38	Gain+Loss	RNASE3 ECRP RNASE2
nsv498822	Chr.14:20881516 - 20945676 on Build GRCh38	Loss	RNASE3 ECRP
nsv428293	Chr.14:20747949 - 21063624 on Build GRCh38	Gain+Loss	RNASE1 NDRG2 LOC101929718 METTL17 RNASE13 EDDM3A SLC39A2 RNASE6 MIR6717 RNASE2 ARHGEF40 RNASE7 RNASE8 EDDM3B RNASE3 TPPP2 ECRP
nsv1044554	Chr.14:20865928 - 20987933 on Build GRCh38	Gain	RNASE3 ECRP RNASE2
nsv563847	Chr.14:20870665 - 21000992 on Build GRCh38	Loss	RNASE3 LOC101929718 METTL17 SLC39A2 ECRP RNASE2
esv3892467	Chr.14:20876009 - 20952929 on Build GRCh38	Gain+Loss	RNASE3 ECRP
nsv832740	Chr.14:20863901 - 21076893 on Build GRCh38	Gain	NDRG2 LOC101929718 METTL17 RNASE13 SLC39A2 MIR6717 RNASE2 ARHGEF40 RNASE7 RNASE8 RNASE3 TPPP2 ECRP
dgv363n67	Chr.14:20875340 - 20955179 on Build GRCh38	Gain	RNASE3 ECRP
nsv436831	Chr.14:20887999 - 20947016 on Build GRCh38	Insertion	RNASE3 ECRP
nsv9121	Chr.14:20873744 - 20958490 on Build GRCh38	Gain+Loss	RNASE3 ECRP RNASE2
esv2673725	Chr.14:20889599 - 20917545 on Build GRCh38	Deletion	RNASE3
esv29488	Chr.14:20881501 - 20955354 on Build GRCh38	Loss	RNASE3 ECRP
nsv983967	Chr.14:20873752 - 20965496 on Build GRCh38	Duplication	RNASE3 ECRP RNASE2
dgv1798n100	Chr.14:20870300 - 20957189 on Build GRCh38	Gain+Loss	RNASE3 ECRP RNASE2
nsv517174	Chr.14:20875005 - 20952929 on Build GRCh38	Gain+Loss	RNASE3 ECRP
nsv1204	Chr.14:20875245 - 20949449 on Build GRCh38	Deletion	RNASE3 ECRP
dgv381e214	Chr.14:20886539 - 20953797 on Build GRCh38	Loss	RNASE3 ECRP
nsv1205	Chr.14:20876553 - 20909051 on Build GRCh38	Insertion	RNASE3
nsv433274	Chr.14:20889996 - 20937726 on Build GRCh38	Loss	RNASE3 ECRP
dgv1799n100	Chr.14:20872480 - 20941810 on Build GRCh38	Loss	RNASE3 ECRP
dgv1802n100	Chr.14:20881449 - 20964296 on Build GRCh38	Loss	RNASE3 ECRP RNASE2
esv3584663	Chr.14:20881447 - 20941822 on Build GRCh38	Loss	RNASE3 ECRP
dgv1801n100	Chr.14:20880514 - 20934425 on Build GRCh38	Gain	RNASE3 ECRP

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

innate immune response in mucosa
RNA catabolic process
antibacterial humoral response
defense response to Gram-positive bacterium
RNA phosphodiester bond hydrolysis

Function(s)

nucleic acid binding
endonuclease activity
ribonuclease activity