Hs02510202_cn

• Gene Symbol: POLR3A
• Assay Reference Genome Location: Chr.10:77982747 on build GRCh38
• Cytoband: 10q22.3

Target Gene Details

• Entrez Gene ID: 11128
• Gene Name: RNA polymerase III subunit A
• Gene Aliases: ADDH, HLD7, RPC1, RPC155, hRPC155
• Location: Chr.10:77975149-78029540 on Build GRCh38
• Assay Gene Location: Within Exon 27

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR3A	NM_007055.3	27	3633	NP_008986.2
	AF021351.1	28	3500	AAB86536.1
	AK026023.1	18	2207
	AK300329.1	28	3550
	AY091461.1			AAM12031.1
	AY091462.1	3	227	AAM12032.1
	BC014399.1	4	339	AAH14399.1
	BC041089.1	27	3594	AAH41089.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv7310	Chr.10:77962983 - 78007707 on Build GRCh38	Deletion	POLR3A

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
transcription from RNA polymerase III promoter
positive regulation of type I interferon production
positive regulation of interferon-beta production
innate immune response
defense response to virus
regulation of mitophagy
positive regulation of protein targeting to mitochondrion

Function(s)

RNA polymerase III activity
DNA binding
chromatin binding
DNA-directed RNA polymerase activity
metal ion binding