Hs02543223_cn

• Gene Symbol: IL2RB
• Assay Reference Genome Location: Chr.22:37126924 on build GRCh38
• Cytoband: 22q12.3

Target Gene Details

• Entrez Gene ID: 3560
• Gene Name: interleukin 2 receptor subunit beta
• Gene Aliases: CD122, IL15RB, P70-75
• Location: Chr.22:37125838-37149922 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
IL2RB	NM_000878.3	10	2959	NP_000869.1
	BC025691.1	10	2942	AAH25691.1
	M26062.1	10	2959	AAA59143.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv829203	Chr.22:36998126 - 37773322 on Build GRCh38	Loss	LGALS2 SSTR3 C1QTNF6 ELFN2 MPST TRIOBP SH3BP1 MFNG CARD10 TST GGA1 RAC2 LOC102724378 LOC101927051 TMPRSS6 CDC42EP1 LOC100506271 IL2RB NOL12 TEX33 CYTH4 LGALS1 PDXP KCTD17
nsv834187	Chr.22:36965603 - 37163260 on Build GRCh38	Loss	TMPRSS6 MPST IL2RB TEX33 LL22NC01-81G9.3 KCTD17 TST
esv34015	Chr.22:36966049 - 37189804 on Build GRCh38	Loss	TMPRSS6 C1QTNF6 MPST IL2RB TEX33 LL22NC01-81G9.3 KCTD17 TST
nsv459882	Chr.22:36967923 - 37161398 on Build GRCh38	Gain	TMPRSS6 MPST IL2RB TEX33 LL22NC01-81G9.3 KCTD17 TST

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
protein complex assembly
signal transduction
viral process
cytokine-mediated signaling pathway
natural killer cell activation
interleukin-2-mediated signaling pathway
negative regulation of apoptotic process
positive regulation of GTPase activity

Function(s)

interleukin-2 receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
interleukin-2 binding