Hs02552292_cn

• Gene Symbol: PSMA2
• Assay Reference Genome Location: Chr.7:42917370 on build GRCh38
• Cytoband: 7p14.1

Target Gene Details

• Entrez Gene ID: 5683
• Gene Name: proteasome subunit alpha 2
• Gene Aliases: HC3, MU, PMSA2, PSC2
• Location: Chr.7:42916861-42932206 on Build GRCh38
• Assay Gene Location: Within Exon 8

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PSMA2	NM_002787.4	8	957	NP_002778.1
	AK290654.1
	BC047697.1	8	911	AAH47697.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv606715	Chr.7:42169735 - 42940343 on Build GRCh38	Gain	MRPL32 GLI3 PSMA2 LINC01448 C7orf25
nsv830979	Chr.7:42806983 - 42987012 on Build GRCh38	Gain	MRPL32 PSMA2 C7orf25

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

MAPK cascade
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
regulation of cellular amino acid metabolic process
response to virus
anaphase-promoting complex-dependent catabolic process
tumor necrosis factor-mediated signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
T cell receptor signaling pathway
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway

Function(s)

threonine-type endopeptidase activity
protein binding