Hs02596727_cn

• Gene Symbol: FLT1
• Assay Reference Genome Location: Chr.13:28301827 on build GRCh38
• Cytoband: 13q12.3

Target Gene Details

• Entrez Gene ID: 2321
• Gene Name: fms related tyrosine kinase 1
• Gene Aliases: FLT, FLT-1, VEGFR-1, VEGFR1
• Location: Chr.13:28300346-28495128 on Build GRCh38
• Assay Gene Location: Within Exon 33

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
FLT1	NM_002019.4	30	5642	NP_002010.2
	XM_017020485.1	29	5528	XP_016875974.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv34052	Chr.13:28074532 - 28352440 on Build GRCh38	Loss	FLT1 FLT3 PAN3 PAN3-AS1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
angiogenesis
response to hypoxia
monocyte chemotaxis
regulation of smooth muscle contraction
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of cell proliferation
positive regulation of phospholipase C activity
positive regulation of phosphatidylinositol 3-kinase signaling
cell migration
peptidyl-tyrosine phosphorylation
cell differentiation
positive regulation of cell migration
intracellular receptor signaling pathway
positive regulation of vascular endothelial growth factor receptor signaling pathway
cellular response to vascular endothelial growth factor stimulus
vascular endothelial growth factor receptor-1 signaling pathway
vascular endothelial growth factor signaling pathway
positive regulation of MAP kinase activity
positive regulation of MAPK cascade
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of angiogenesis
protein autophosphorylation
vascular endothelial growth factor receptor signaling pathway
blood vessel morphogenesis
embryonic morphogenesis
positive regulation of smooth muscle cell proliferation

Function(s)

transmembrane receptor protein tyrosine kinase activity
vascular endothelial growth factor-activated receptor activity
protein binding
ATP binding
growth factor binding
VEGF-A-activated receptor activity
VEGF-B-activated receptor activity
placental growth factor-activated receptor activity