Hs02611849_cn

• Gene Symbol: CDT1
• Assay Reference Genome Location: Chr.16:88804668 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 81620
• Gene Name: chromatin licensing and DNA replication factor 1
• Gene Aliases: DUP, RIS2
• Location: Chr.16:88803778-88809258 on Build GRCh38
• Assay Gene Location: Overlaps Exon 2 - Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDT1	NM_030928.3			NP_112190.2
	AB053172.1			BAB61878.1
	AF321125.1			AAG45181.1
	BC000137.2			AAH00137.2
	BC008676.1			AAH08676.1
	BC008860.2			AAH08860.2
	BC009410.1			AAH09410.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv573677	Chr.16:88764428 - 88805821 on Build GRCh38	Loss	PIEZO1 CDT1
dgv5313n54	Chr.16:88795879 - 88806103 on Build GRCh38	Loss	CDT1
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	TRAPPC2L CDH15 SLC22A31 ACSF3 PIEZO1 LOC400558 CTU2 APRT LOC105371409 GALNS ZNF778 LOC101927793 LOC100129697 LINC00304 CBFA2T3 MIR4722 PABPN1L LOC107987238 LOC100289580 LOC339059 CDT1
nsv457617	Chr.16:88801844 - 88829729 on Build GRCh38	Gain	GALNS LOC107987238 APRT CDT1
dgv3064n100	Chr.16:88683753 - 88846491 on Build GRCh38	Gain	GALNS SNAI3 MIR4722 SNAI3-AS1 PIEZO1 CTU2 LOC107987238 LOC100289580 APRT RNF166 LOC339059 CDT1
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	TRAPPC2L CDH15 SLC22A31 ACSF3 PIEZO1 LOC400558 APRT LOC105371409 GALNS ZNF778 LOC105371414 LOC100287036 LOC101927793 LOC100129697 LINC00304 CBFA2T3 PABPN1L LOC107987238 LOC100289580 ANKRD11 LOC339059 CDT1
nsv952071	Chr.16:88790893 - 89019992 on Build GRCh38	Deletion	GALNS TRAPPC2L LOC101927793 LOC100129697 CBFA2T3 PABPN1L LOC107987238 APRT LOC105371409 CDT1
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	DBNDD1 LOC107984817 SLC22A31 GAS8-AS1 SPATA33 VPS9D1 PRDM7 LOC400558 MC1R VPS9D1-AS1 ZNF778 LOC101927793 RPL13 FANCA PABPN1L RNF166 CYBA CDT1 TRAPPC2L CTU2 LOC105371414 CPNE7 SNORD68 FAM157C MVD URAHP TUBB3 SNAI3-AS1 IL17C TCF25 LOC339059 CDK10 LOC101927817 CDH15 CHMP1A ACSF3 CENPBD1 APRT GALNS LOC100129697 LINC00304 CBFA2T3 SNAI3 MIR4722 LOC100289580 DPEP1 SPATA2L ZNF276 DEF8 LOC105371419 PIEZO1 TUBB8P7 LOC105371409 AFG3L1P LOC100287036 SPG7 SPIRE2 GAS8 LOC107987238 ANKRD11
nsv1063441	Chr.16:88767066 - 88861882 on Build GRCh38	Loss	GALNS TRAPPC2L PIEZO1 LOC107987238 APRT CDT1
dgv37n68	Chr.16:88767460 - 88944903 on Build GRCh38	Loss	GALNS TRAPPC2L LOC101927793 LOC100129697 CBFA2T3 PIEZO1 PABPN1L LOC107987238 APRT LOC105371409 CDT1
esv3639555	Chr.16:88745961 - 88899576 on Build GRCh38	Gain	GALNS TRAPPC2L LOC101927793 CBFA2T3 PIEZO1 PABPN1L LOC107987238 APRT CDT1
nsv1061256	Chr.16:88711587 - 89013365 on Build GRCh38	Gain	TRAPPC2L PIEZO1 CTU2 APRT LOC105371409 GALNS LOC101927793 LOC100129697 CBFA2T3 MIR4722 PABPN1L LOC107987238 LOC100289580 LOC339059 CDT1
nsv573712	Chr.16:88796728 - 88809084 on Build GRCh38	Loss	CDT1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

DNA replication checkpoint
G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
DNA replication
regulation of DNA-dependent DNA replication initiation
regulation of nuclear cell cycle DNA replication

Function(s)

DNA binding
protein binding