Hs02611849_cn

• Gene Symbol: CDT1
• Assay Reference Genome Location: Chr.16:88804668 on build GRCh38
• Cytoband: 16q24.3

Target Gene Details

• Entrez Gene ID: 81620
• Gene Name: chromatin licensing and DNA replication factor 1
• Gene Aliases: DUP, RIS2
• Location: Chr.16:88803778-88809258 on Build GRCh38
• Assay Gene Location: Overlaps Exon 2 - Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDT1	NM_030928.3			NP_112190.2
	AB053172.1			BAB61878.1
	AF321125.1			AAG45181.1
	BC000137.2			AAH00137.2
	BC008676.1			AAH08676.1
	BC008860.2			AAH08860.2
	BC009410.1			AAH09410.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv5313n54	Chr.16:88795879 - 88806103 on Build GRCh38	Loss	CDT1
nsv573677	Chr.16:88764428 - 88805821 on Build GRCh38	Loss	PIEZO1 CDT1
nsv1063024	Chr.16:88707330 - 89238482 on Build GRCh38	Gain	ZNF778 LOC105371409 LOC101927793 CDH15 LOC400558 APRT LINC00304 ACSF3 GALNS LOC100289580 PIEZO1 LOC100129697 LOC339059 MIR4722 PABPN1L TRAPPC2L CBFA2T3 CTU2 LOC107987238 CDT1 SLC22A31
nsv471115	Chr.16:88801844 - 89197442 on Build GRCh38	Loss	LOC105371409 LOC101927793 CDH15 LOC400558 APRT LINC00304 ACSF3 GALNS LOC100129697 PABPN1L TRAPPC2L CBFA2T3 LOC107987238 CDT1 SLC22A31
dgv3064n100	Chr.16:88683753 - 88846491 on Build GRCh38	Gain	PIEZO1 LOC339059 MIR4722 SNAI3-AS1 APRT CTU2 SNAI3 LOC107987238 CDT1 RNF166 GALNS LOC100289580
nsv573674	Chr.16:88738775 - 89325907 on Build GRCh38	Gain	ZNF778 LOC105371409 LOC101927793 CDH15 LOC400558 APRT LINC00304 ACSF3 LOC100287036 GALNS LOC100289580 PIEZO1 LOC100129697 LOC339059 LOC105371414 PABPN1L TRAPPC2L CBFA2T3 ANKRD11 LOC107987238 CDT1 SLC22A31
nsv952071	Chr.16:88790893 - 89019992 on Build GRCh38	Deletion	LOC100129697 LOC105371409 LOC101927793 PABPN1L TRAPPC2L CBFA2T3 APRT LOC107987238 CDT1 GALNS
nsv482951	Chr.16:88633593 - 90228345 on Build GRCh38	Loss	LOC107984817 TUBB8P7 SPATA33 SPATA2L URAHP LINC00304 TCF25 GALNS CENPBD1 PIEZO1 VPS9D1-AS1 PABPN1L TRAPPC2L CBFA2T3 CTU2 ANKRD11 FANCA IL17C DBNDD1 CPNE7 APRT MVD RNF166 LOC100289580 CHMP1A ZNF276 SPIRE2 LOC339059 LOC105371419 GAS8 CDT1 ZNF778 RPL13 DEF8 CDK10 LOC101927793 MC1R LOC400558 SNORD68 ACSF3 LOC100287036 LOC100129697 AFG3L1P MIR4722 SNAI3-AS1 SNAI3 VPS9D1 LOC107987238 TUBB3 CYBA SPG7 LOC105371409 CDH15 PRDM7 FAM157C LOC105371414 GAS8-AS1 LOC101927817 SLC22A31 DPEP1
nsv1063441	Chr.16:88767066 - 88861882 on Build GRCh38	Loss	PIEZO1 TRAPPC2L APRT LOC107987238 CDT1 GALNS
dgv37n68	Chr.16:88767460 - 88944903 on Build GRCh38	Loss	PIEZO1 LOC100129697 LOC105371409 LOC101927793 PABPN1L TRAPPC2L CBFA2T3 APRT LOC107987238 CDT1 GALNS
esv3639555	Chr.16:88745961 - 88899576 on Build GRCh38	Gain	PIEZO1 LOC101927793 PABPN1L TRAPPC2L CBFA2T3 APRT LOC107987238 CDT1 GALNS
nsv573712	Chr.16:88796728 - 88809084 on Build GRCh38	Loss	CDT1
dgv3065n100	Chr.16:88711587 - 88927172 on Build GRCh38	Gain	LOC101927793 APRT GALNS LOC100289580 PIEZO1 LOC339059 MIR4722 PABPN1L TRAPPC2L CBFA2T3 CTU2 LOC107987238 CDT1

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

DNA replication checkpoint
G1/S transition of mitotic cell cycle
regulation of transcription involved in G1/S transition of mitotic cell cycle
DNA replication
regulation of DNA-dependent DNA replication initiation
regulation of nuclear cell cycle DNA replication

Function(s)

DNA binding
protein binding