Hs02647208_cn

• Gene Symbol: EPX
• Assay Reference Genome Location: Chr.17:58192771 on build GRCh38
• Cytoband: 17q22

Target Gene Details

• Entrez Gene ID: 8288
• Gene Name: eosinophil peroxidase
• Gene Aliases: EPO, EPP, EPX-PEN, EPXD
• Location: Chr.17:58192724-58205174 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EPX	NM_000502.5	1	48	NP_000493.1
	BM147889.1	1	48

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv517229	Chr.17:58176226 - 58373163 on Build GRCh38	Gain+Loss	RNF43 MIR142 MKS1 EPX MIR4736 SUPT4H1 MPO TSPOAP1-AS1 TSPOAP1 LPO
nsv457858	Chr.17:58180623 - 58212973 on Build GRCh38	Loss	MKS1 EPX

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

peroxidase

Gene Ontology Categories:

Process(es)

defense response to nematode
response to oxidative stress
negative regulation of interleukin-10 production
negative regulation of interleukin-5 production
positive regulation of interleukin-4 production
hydrogen peroxide catabolic process
oxidation-reduction process
eosinophil migration
cellular oxidant detoxification

Function(s)

peroxidase activity
heme binding
metal ion binding