Hs02679781_cn

• Gene Symbol: ADRA2B
• Assay Reference Genome Location: Chr.2:96115906 on build GRCh38
• Cytoband: 2q11.2

Target Gene Details

• Entrez Gene ID: 151
• Gene Name: adrenoceptor alpha 2B
• Gene Aliases: ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, FAME2, alpha-2BAR
• Location: Chr.2:96112875-96116245 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ADRA2B	NM_000682.6	1	340	NP_000673.2
	BC133021.1	1	340
	BC136537.1	1	340

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv607e201	Chr.2:95855884 - 97561622 on Build GRCh38	Deletion	SNRNP200 LMAN2L ANKRD23 NCAPH ARID5A ANKRD39 ANKRD36B DUSP2 MIR3127 LOC653924 TMEM127 LOC105373496 ADRA2B ASTL FAHD2CP FER1L5 NEURL3 ANKRD36 LOC100506076 ANKRD36C KANSL3 FAHD2B LOC100506123 STARD7 FAM178B LOC107984110 LOC101927053 GPAT2 ITPRIPL1 CNNM4 SEMA4C CNNM3 CIAO1 LOC105373495 STARD7-AS1
nsv2834	Chr.2:96107177 - 96119371 on Build GRCh38	Deletion	ADRA2B
dgv4009n100	Chr.2:96072837 - 96159625 on Build GRCh38	Gain	ADRA2B ASTL DUSP2
nsv1135873	Chr.2:95981454 - 97579645 on Build GRCh38	Deletion	SNRNP200 LMAN2L ANKRD23 NCAPH ARID5A ANKRD39 ANKRD36B DUSP2 MIR3127 LOC653924 TMEM127 LOC105373496 ADRA2B ASTL FAHD2CP FER1L5 NEURL3 ANKRD36 LOC100506076 ANKRD36C KANSL3 FAHD2B LOC100506123 STARD7 FAM178B LOC107984110 LOC101927053 GPAT2 ITPRIPL1 CNNM4 SEMA4C CNNM3 CIAO1 LOC105373495 STARD7-AS1
esv3425717	Chr.2:95859900 - 97515905 on Build GRCh38	Duplication	SNRNP200 LMAN2L ANKRD23 NCAPH ARID5A ANKRD39 ANKRD36B DUSP2 MIR3127 LOC653924 TMEM127 LOC105373496 ADRA2B ASTL FAHD2CP FER1L5 NEURL3 ANKRD36 LOC100506076 ANKRD36C KANSL3 FAHD2B LOC100506123 STARD7 FAM178B LOC107984110 LOC101927053 GPAT2 ITPRIPL1 CNNM4 SEMA4C CNNM3 CIAO1 LOC105373495 STARD7-AS1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

G-protein coupled receptor

Gene Ontology Categories:

Process(es)

regulation of smooth muscle contraction
G-protein coupled receptor signaling pathway
cell-cell signaling
negative regulation of norepinephrine secretion
regulation of vasoconstriction
platelet activation
activation of protein kinase B activity
negative regulation of epinephrine secretion
epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
positive regulation of neuron differentiation
adenylate cyclase-activating adrenergic receptor signaling pathway
activation of MAPK activity by adrenergic receptor signaling pathway

Function(s)

alpha2-adrenergic receptor activity
protein binding
epinephrine binding