Hs02681101_cn

• Gene Symbol: GLUL
• Assay Reference Genome Location: Chr.1:182383757 on build GRCh38
• Cytoband: 1q25.3

Target Gene Details

• Entrez Gene ID: 2752
• Gene Name: glutamate-ammonia ligase
• Gene Aliases: GLNS, GS, PIG43, PIG59
• Location: Chr.1:182378093-182392206 on Build GRCh38
• Assay Gene Location: Within Exon 9

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
GLUL	NM_001033044.3	7	2311	NP_001028216.1
	NM_001033056.3	7	2013	NP_001028228.1
	NM_002065.6	8	2667	NP_002056.2
	XM_006711278.1	7	2374	XP_006711341.1
	AL161952.1	2	4132	CAB82304.1
	AY947343.1	7	1871
	BC011700.2	7	1879	AAH11700.1
	BC011852.2	7	1890	AAH11852.1
	BC018992.1	8	2230	AAH18992.1
	BC051726.1	7	3076	AAH51726.1
	BX537384.1	7	1895	CAD97626.1
	S70290.1	6	1770	AAB30693.1
	X59834.1	7	1879	CAA42495.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv548358	Chr.1:182110851 - 183151893 on Build GRCh38	Gain	LINC01344 RNASEL GLUL DHX9 LINC00272 NPL LAMC1 RGSL1 RGS16 SHCBP1L LOC284648 LOC105371644 ZNF648 RGS8 LOC647070 TEDDM1

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

ligase

Gene Ontology Categories:

Process(es)

neurotransmitter uptake
glutamate catabolic process
glutamine biosynthetic process
cell proliferation
cellular amino acid biosynthetic process
cellular response to starvation
response to glucose
ammonia assimilation cycle
positive regulation of insulin secretion
positive regulation of epithelial cell proliferation
protein homooligomerization
positive regulation of synaptic transmission, glutamatergic

Function(s)

magnesium ion binding
glutamate decarboxylase activity
glutamate-ammonia ligase activity
protein binding
ATP binding
glutamate binding
manganese ion binding
identical protein binding
dynein light chain binding