Hs02712455_cn

• Gene Symbol: CYB561A3
• Assay Reference Genome Location: Chr.11:61349765 on build GRCh38
• Cytoband: 11q12.2

Target Gene Details

• Entrez Gene ID: 220002
• Gene Name: cytochrome b561 family member A3
• Gene Aliases: CYBASC3, LCYTB
• Location: Chr.11:61348748-61362299 on Build GRCh38
• Assay Gene Location: Within Exon 10

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CYB561A3	NM_001161452.1	5	1539	NP_001154924.1
	NM_001161454.1	8	2194	NP_001154926.1
	NM_001300763.1			NP_001287692.1
	NM_153611.4	7	2025	NP_705839.3
	XM_011544821.1			XP_011543123.1
	XM_011544823.1			XP_011543125.1
	XM_017017345.1			XP_016872834.1
	XM_017017346.1			XP_016872835.1
	XM_017017347.1			XP_016872836.1
	AK024953.1	4	989
	AK025870.1	3	872
	AK056751.1	7	2016
	AK075559.1	7	1626	BAC11698.1
	AK310976.1	6	1400
	AL833374.1	3	856
	BC004391.1	7	1999	AAH04391.1
	BC014045.2	7	1835	AAH14045.2
	BC047710.1	7	1544	AAH47710.1
	BM692535.1
	BP296553.1	1	533

Target Gene Details

• Entrez Gene ID: 26007
• Gene Name: triokinase and FMN cyclase
• Gene Aliases: DAK, NET45
• Location: Chr.11:61333182-61353426 on Build GRCh38
• Assay Gene Location: Within Intron 20

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
TKFC	XM_017017518.1			XP_016873007.1
	XM_017017522.1			XP_016873011.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428259	Chr.11:61049513 - 61356164 on Build GRCh38	Gain+Loss	CYB561A3 PGA4 TKFC DDB1 VPS37C PGA5 LOC105369325 VWCE CD5 PGA3
nsv832177	Chr.11:61185118 - 61356164 on Build GRCh38	Loss	CYB561A3 PGA4 TKFC DDB1 PGA5 VWCE PGA3

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

reductase, cyclase

Gene Ontology Categories:

Process(es)

oxidation-reduction process
glycerol metabolic process
negative regulation of MDA-5 signaling pathway
cellular carbohydrate metabolic process
innate immune response
regulation of innate immune response
carbohydrate phosphorylation
fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

Function(s)

protein binding
oxidoreductase activity
metal ion binding
glycerone kinase activity
ATP binding
FAD-AMP lyase (cyclizing) activity
triokinase activity