Hs02768943_cn

• Gene Symbol: XCL1
• Assay Reference Genome Location: Chr.1:168581738 on build GRCh38
• Cytoband: 1q24.2

Target Gene Details

• Entrez Gene ID: 6375
• Gene Name: X-C motif chemokine ligand 1
• Gene Aliases: ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCM1A, SCYC1
• Location: Chr.1:168574128-168582077 on Build GRCh38
• Assay Gene Location: Within Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
XCL1	NM_002995.2	3	1028	NP_002986.1
	D43768.1	3	883	BAA07825.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831836	Chr.1:168569541 - 168747718 on Build GRCh38	Gain+Loss	XCL1 DPT

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

cytokine, intercellular signal molecule

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
monocyte chemotaxis
positive regulation of leukocyte chemotaxis
negative regulation of T cell cytokine production
positive regulation of T cell cytokine production
negative regulation of T-helper 1 type immune response
signal transduction
G-protein coupled receptor signaling pathway
cell-cell signaling
response to virus
positive regulation of T cell chemotaxis
neutrophil chemotaxis
negative regulation of interferon-gamma production
negative regulation of interleukin-2 production
positive regulation of interleukin-10 production
mature natural killer cell chemotaxis
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of GTPase activity
negative regulation of transcription, DNA-templated
regulation of inflammatory response
positive regulation of inflammatory response
release of sequestered calcium ion into cytosol
positive regulation of release of sequestered calcium ion into cytosol
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to interleukin-4
cellular response to tumor necrosis factor
cellular response to transforming growth factor beta stimulus
positive regulation of transforming growth factor beta production
positive regulation of granzyme B production
positive regulation of neutrophil chemotaxis
positive regulation of thymocyte migration
positive regulation of natural killer cell chemotaxis
positive regulation of granzyme A production
negative regulation of T-helper 1 cell activation
positive regulation of B cell chemotaxis
positive regulation of T-helper 2 cell cytokine production
positive regulation of T-helper 1 cell cytokine production
positive regulation of immunoglobulin production in mucosal tissue
negative regulation of CD4-positive, alpha-beta T cell proliferation
positive regulation of CD4-positive, alpha-beta T cell proliferation
positive regulation of CD8-positive, alpha-beta T cell proliferation

Function(s)

chemokine activity
chemokine receptor binding
protein homodimerization activity
CCR chemokine receptor binding