Hs02808987_cn

• Gene Symbol: PPP1R16A
• Assay Reference Genome Location: Chr.8:144498756 on build GRCh38
• Cytoband: 8q24.3

Target Gene Details

• Entrez Gene ID: 84988
• Gene Name: protein phosphatase 1 regulatory subunit 16A
• Gene Aliases: MYPT3
• Location: Chr.8:144477987-144502121 on Build GRCh38
• Assay Gene Location: Overlaps Intron 5 - Exon 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP1R16A	XM_005272350.2			XP_005272407.1
	XM_011517349.2			XP_011515651.1
	XM_017013912.1			XP_016869401.1
	XM_017013913.1			XP_016869402.1
	XM_017013914.1			XP_016869403.1
	XM_017013915.1			XP_016869404.1
	AK090471.1	4	2430	BAC03452.1
	BC007854.2			AAH07854.1
	BC049841.1			AAH49841.1
	BC053506.1			AAH53506.1
	BT006845.1			AAP35491.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv470249	Chr.8:143889098 - 144519234 on Build GRCh38	Loss	GRINA CYC1 GPAA1 MFSD3 FBXL6 MIR6893 EXOSC4 TMEM249 OPLAH HGH1 PLEC BOP1 SHARPIN TONSL-AS1 GPT CPSF1 RECQL4 MIR6846 LOC101928902 SCRT1 MIR661 SLC39A4 MIR6849 PARP10 MIR939 SCX CYHR1 MIR6847 TONSL LOC101928953 FOXH1 MIR7112 SLC52A2 MROH1 ADCK5 HSF1 DGAT1 KIFC2 MIR6848 VPS28 PPP1R16A WDR97 SMPD5 MIR1234 LRRC14 MAF1 SPATC1
nsv612951	Chr.8:144479830 - 144677692 on Build GRCh38	Loss	RECQL4 C8orf82 MFSD3 LOC101928953 ARHGAP39 PPP1R16A LRRC24 LRRC14 GPT
nsv831489	Chr.8:144342140 - 144544026 on Build GRCh38	Loss	C8orf82 MFSD3 FBXL6 MIR6893 TMEM249 TONSL-AS1 GPT CPSF1 RECQL4 LOC101928902 SLC39A4 MIR6849 ARHGAP39 LRRC24 MIR939 CYHR1 TONSL LOC101928953 FOXH1 SLC52A2 ADCK5 KIFC2 VPS28 PPP1R16A MIR1234 LRRC14
dgv12439n54	Chr.8:144438306 - 144525122 on Build GRCh38	Loss	RECQL4 CYHR1 MFSD3 TONSL LOC101928953 FOXH1 KIFC2 PPP1R16A LRRC24 TONSL-AS1 LRRC14 GPT
dgv1207n67	Chr.8:144498396 - 144532417 on Build GRCh38	Gain	RECQL4 C8orf82 MFSD3 LOC101928953 ARHGAP39 PPP1R16A LRRC24 LRRC14 GPT
nsv612955	Chr.8:144494912 - 144502322 on Build GRCh38	Loss	LOC101928953 PPP1R16A GPT
nsv482126	Chr.8:144496726 - 144502120 on Build GRCh38	Gain	LOC101928953 PPP1R16A
dgv907n27	Chr.8:144416180 - 144525122 on Build GRCh38	Loss	CYHR1 MFSD3 MIR6893 TONSL LOC101928953 FOXH1 TONSL-AS1 GPT RECQL4 SLC39A4 KIFC2 VPS28 PPP1R16A LRRC24 LRRC14
dgv12434n54	Chr.8:144270080 - 144516801 on Build GRCh38	Loss	MFSD3 FBXL6 MIR6893 TMEM249 BOP1 TONSL-AS1 GPT CPSF1 RECQL4 LOC101928902 SCRT1 SLC39A4 MIR6849 MIR939 CYHR1 TONSL LOC101928953 FOXH1 SLC52A2 ADCK5 HSF1 DGAT1 KIFC2 MIR6848 VPS28 PPP1R16A MIR1234
dgv12442n54	Chr.8:144492696 - 144516381 on Build GRCh38	Loss	RECQL4 MFSD3 LOC101928953 PPP1R16A GPT
nsv515809	Chr.8:143904439 - 144519234 on Build GRCh38	Gain+Loss	GRINA CYC1 GPAA1 MFSD3 FBXL6 MIR6893 EXOSC4 TMEM249 OPLAH HGH1 PLEC BOP1 SHARPIN TONSL-AS1 GPT CPSF1 RECQL4 MIR6846 LOC101928902 SCRT1 MIR661 SLC39A4 MIR6849 PARP10 MIR939 SCX CYHR1 MIR6847 TONSL LOC101928953 FOXH1 MIR7112 SLC52A2 MROH1 ADCK5 HSF1 DGAT1 KIFC2 MIR6848 VPS28 PPP1R16A WDR97 SMPD5 MIR1234 LRRC14 MAF1 SPATC1
nsv612940	Chr.8:144436292 - 144613673 on Build GRCh38	Loss	CYHR1 C8orf82 MFSD3 TONSL LOC101928953 FOXH1 TONSL-AS1 GPT RECQL4 ARHGAP39 KIFC2 PPP1R16A LRRC24 LRRC14
nsv428208	Chr.8:144041826 - 144722291 on Build GRCh38	Gain	CYC1 GPAA1 C8orf82 MFSD3 FBXL6 MIR6893 ZNF251 EXOSC4 TMEM249 OPLAH HGH1 BOP1 SHARPIN TONSL-AS1 GPT CPSF1 RECQL4 MIR6846 LOC101928902 SCRT1 SLC39A4 MIR6849 ARHGAP39 LRRC24 MIR939 SCX CYHR1 MIR6847 TONSL LOC101928953 FOXH1 MIR7112 SLC52A2 MROH1 ADCK5 HSF1 DGAT1 KIFC2 MIR6848 VPS28 PPP1R16A WDR97 SMPD5 MIR1234 LRRC14 MAF1 SPATC1
esv29999	Chr.8:144456732 - 144525122 on Build GRCh38	Loss	RECQL4 CYHR1 MFSD3 LOC101928953 FOXH1 KIFC2 PPP1R16A LRRC24 LRRC14 GPT

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

phosphatase modulator

Gene Ontology Categories:

Process(es)

regulation of catalytic activity

Function(s)

protein binding
protein phosphatase type 1 regulator activity