Hs02865536_cn

• Gene Symbol: LTA4H
• Assay Reference Genome Location: Chr.12:96001054 on build GRCh38
• Cytoband: 12q23.1

Target Gene Details

• Entrez Gene ID: 4048
• Gene Name: leukotriene A4 hydrolase
• Gene Aliases: -
• Location: Chr.12:96000753-96043520 on Build GRCh38
• Assay Gene Location: Within Exon 21

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LTA4H	NM_000895.2	19	1913	NP_000886.1
	NM_001256643.1	19	1844	NP_001243572.1
	NM_001256644.1	18	1761	NP_001243573.1
	NR_132659.1	19	1913
	XM_005268871.1	18	1820	XP_005268928.1
	AB209740.1	19	5888	BAD92977.1
	AI582379.1	1	250
	AK298017.1	18	1761
	AK301308.1	19	1722
	BC032528.1	19	1830	AAH32528.1
	BC036555.1	6	1662	AAH36555.1
	BX647158.1	19	1801
	CR457068.1	19	1771	CAG33349.1
	J02959.1	19	1801	AAA36177.1
	J03459.1	19	1839	AAA36176.1
	R41544.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3630445	Chr.12:95990852 - 96016216 on Build GRCh38	Gain	HAL LTA4H
nsv523292	Chr.12:95992360 - 96015423 on Build GRCh38	Gain	HAL LTA4H

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Gene Ontology Categories:

Process(es)

proteolysis
leukotriene metabolic process
response to zinc ion
leukotriene biosynthetic process
peptide catabolic process
response to peptide hormone
Type I pneumocyte differentiation

Function(s)

aminopeptidase activity
epoxide hydrolase activity
leukotriene-A4 hydrolase activity
protein binding
peptidase activity
zinc ion binding
peptide binding
poly(A) RNA binding
metalloaminopeptidase activity