Hs02870321_cn

• Gene Symbol: RANGAP1
• Assay Reference Genome Location: Chr.22:41301655 on build GRCh38
• Cytoband: 22q13.2

Target Gene Details

• Entrez Gene ID: 5905
• Gene Name: Ran GTPase activating protein 1
• Gene Aliases: Fug1, RANGAP, SD
• Location: Chr.22:41244777-41302213 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
RANGAP1	NM_001317930.1			NP_001304859.1
	BC041396.2			AAH41396.1

Target Gene Details

• Entrez Gene ID: 23264
• Gene Name: zinc finger CCCH-type containing 7B
• Gene Aliases: RoXaN
• Location: Chr.22:41301503-41360147 on Build GRCh38
• Assay Gene Location: Within Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
ZC3H7B	NM_017590.5	1	153	NP_060060.3
	XM_011530016.2	1	134	XP_011528318.1
	AF188530.1			AAF05541.1
	AK023849.1
	AK225891.1	1	126
	AK315009.1	1	94
	BC152558.1	1	131

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv516925	Chr.22:41252498 - 41585953 on Build GRCh38	Loss	PMM1 TOB2 TEF ZC3H7B POLR3H MIR6889 ACO2 LOC105373044 CSDC2 LOC100996598 RANGAP1 PHF5A
nsv834207	Chr.22:41282650 - 41463790 on Build GRCh38	Loss	TOB2 TEF ZC3H7B LOC100996598 RANGAP1 PHF5A
nsv3638	Chr.22:41285245 - 41309688 on Build GRCh38	Insertion	ZC3H7B RANGAP1
nsv459888	Chr.22:41231539 - 41454496 on Build GRCh38	Gain	CHADL TOB2 TEF ZC3H7B MIR6889 LOC100996598 RANGAP1
dgv772n67	Chr.22:41290675 - 41308013 on Build GRCh38	Gain	ZC3H7B RANGAP1
nsv829242	Chr.22:41301601 - 41303153 on Build GRCh38	Gain	ZC3H7B RANGAP1
nsv524585	Chr.22:40993505 - 41794305 on Build GRCh38	Loss	CHADL PMM1 POLR3H LOC105373044 XRCC6 SNU13 MEI1 CSDC2 EP300-AS1 PHF5A TOB2 TEF ZC3H7B DESI1 MIR6889 ACO2 EP300 MIR1281 SNORD140 C22orf46 L3MBTL2 LOC100996598 RANGAP1
nsv817997	Chr.22:41244293 - 41366866 on Build GRCh38	Gain	ZC3H7B MIR6889 RANGAP1

More Information

• Set Membership: Intragenic, Exonic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

GTPase-activating protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

sister chromatid cohesion
signal transduction
protein sumoylation
positive regulation of GTPase activity
negative regulation of protein export from nucleus
response to axon injury
cell-cell adhesion
cellular response to vasopressin
viral process

Function(s)

GTPase activator activity
protein binding
Ran GTPase binding
ubiquitin protein ligase binding
cadherin binding involved in cell-cell adhesion
poly(A) RNA binding
metal ion binding