Hs02889745_cn

• Gene Symbol: PPP1R8
• Assay Reference Genome Location: Chr.1:27850252 on build GRCh38
• Cytoband: 1p35.3

Target Gene Details

• Entrez Gene ID: 5511
• Gene Name: protein phosphatase 1 regulatory subunit 8
• Gene Aliases: ARD-1, ARD1, NIPP-1, NIPP1, PRO2047
• Location: Chr.1:27830741-27851672 on Build GRCh38
• Assay Gene Location: Within Exon 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP1R8	NM_002713.3	6	1138	NP_002704.1
	NM_014110.4	7	957	NP_054829.2
	NM_138558.2	7	1239	NP_612568.1
	XM_017001594.1	6	658	XP_016857083.1
	AF061958.1	7	885	AAD31541.1
	AF061959.1	7	1040	AAD31542.1
	AF126488.1	7	873	AAD22486.1
	AK292077.1	7	885
	AK297771.1	6	664
	AK304619.1
	AK307570.1	7	933
	AK313814.1	6	644
	AX775985.1	7	873	CAE11692.1
	BC001597.1	6	765	AAH01597.1
	BC013360.2	6	815	AAH13360.1
	BC093017.1	7	877	AAH93017.1
	BI459680.1
	CR450309.1	2	190	CAG29305.1
	DQ223931.1	4	418	ABB04281.1
	U14575.1	6	1125	AAA64749.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv509069	Chr.1:27817460 - 27905956 on Build GRCh38	Insertion	RPA2 STX12 THEMIS2 SCARNA1 PPP1R8

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

RNA splicing factor

Gene Ontology Categories:

Process(es)

transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA processing
RNA catabolic process
cell proliferation
RNA splicing
negative regulation of catalytic activity
RNA phosphodiester bond hydrolysis

Function(s)

DNA binding
RNA binding
endonuclease activity
protein serine/threonine phosphatase inhibitor activity
protein binding
protein phosphatase type 1 regulator activity
ribonuclease E activity