Hs02924821_cn

• Gene Symbol: AMD1
• Assay Reference Genome Location: Chr.6:110815022 on build GRCh38
• Cytoband: 6q21

Target Gene Details

• Entrez Gene ID: 262
• Gene Name: adenosylmethionine decarboxylase 1
• Gene Aliases: ADOMETDC, AMD, SAMDC
• Location: Chr.6:110814621-110895713 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AMD1	NM_001287215.1			NP_001274144.1
	AK304351.1

Target Gene Details

• Entrez Gene ID: 23097
• Gene Name: cyclin dependent kinase 19
• Gene Aliases: CDC2L6, CDK11, bA346C16.3
• Location: Chr.6:110609978-110816531 on Build GRCh38
• Assay Gene Location: Overlaps Intron 3 - Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CDK19	NM_001300960.1			NP_001287889.1
	NM_001300963.1			NP_001287892.1
	NM_001300964.1			NP_001287893.1
	NM_015076.4			NP_055891.1
	XM_011535630.2			XP_011533932.1
	XM_011535631.2			XP_011533933.1
	XM_017010587.1			XP_016866076.1
	XM_017010588.1			XP_016866077.1
	AB028951.2			BAA82980.2
	AJ420571.1
	AK292360.1
	AY028424.1			AAK27731.1
	BC024247.1			AAH24247.1
	BC037289.1			AAH37289.1
	DB030002.1
	JX028238.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1032572	Chr.6:110800096 - 111060820 on Build GRCh38	Gain	RPF2 AMD1 GTF3C6 CDK19 GSTM2P1
nsv830773	Chr.6:110813116 - 110985229 on Build GRCh38	Loss	RPF2 AMD1 GTF3C6 CDK19

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

decarboxylase, non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

S-adenosylmethioninamine biosynthetic process
polyamine metabolic process
spermine biosynthetic process
spermidine biosynthetic process
S-adenosylmethionine metabolic process
protein phosphorylation
positive regulation of apoptotic process
positive regulation of inflammatory response
regulation of cell cycle
cellular response to lipopolysaccharide

Function(s)

adenosylmethionine decarboxylase activity
putrescine binding
cyclin-dependent protein serine/threonine kinase activity
ATP binding
enzyme binding