Hs03035644_cn

• Gene Symbol: MPL
• Assay Reference Genome Location: Chr.1:43339526 on build GRCh38
• Cytoband: 1p34.2

Target Gene Details

• Entrez Gene ID: 4352
• Gene Name: MPL proto-oncogene, thrombopoietin receptor
• Gene Aliases: C-MPL, CD110, MPLV, THCYT2, TPOR
• Location: Chr.1:43336875-43354464 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MPL	NM_005373.2	4	692	NP_005364.1
	XM_017001320.1	3	1792	XP_016856809.1
	DQ234353.1	4	626	ABB29982.1
	M90102.1	4	647	AAA69971.1
	M90103.1	4	647	AAA69972.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv546128	Chr.1:43301467 - 43451738 on Build GRCh38	Loss	MED8 SZT2 HYI ELOVL1 MPL TIE1 MIR6734 MIR6735 CDC20

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

cell surface receptor signaling pathway
cell proliferation
thrombopoietin-mediated signaling pathway

Function(s)

transmembrane signaling receptor activity
protein binding
thrombopoietin receptor activity