Hs03057144_cn

• Gene Symbol: AKAP13
• Assay Reference Genome Location: Chr.15:85380596 on build GRCh38
• Cytoband: 15q25.3

Target Gene Details

• Entrez Gene ID: 11214
• Gene Name: A-kinase anchoring protein 13
• Gene Aliases: AKAP-13, AKAP-Lbc, ARHGEF13, BRX, HA-3, Ht31, LBC, PRKA13, PROTO-LB, PROTO-LBC, c-lbc, p47
• Location: Chr.15:85380616-85749358 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
AKAP13	NM_006738.5			NP_006729.4
	NM_007200.4			NP_009131.2
	AB055890.1			BAB62913.1
	AK125331.1
	BC050312.1			AAH50312.1

Target Gene Details

• Entrez Gene ID: 102465803
• Gene Name: microRNA 7706
• Gene Aliases: hsa-mir-7706
• Location: Chr.15:85380596-85380662 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
MIR7706	NR_106993.1
	KC832804.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
dgv4692n54	Chr.15:85235254 - 85600273 on Build GRCh38	Gain	AKAP13 MIR7706 GOLGA6L3
esv2761699	Chr.15:85236347 - 85569198 on Build GRCh38	Gain	AKAP13 MIR7706 GOLGA6L3
nsv974618	Chr.15:85379452 - 85384895 on Build GRCh38	Duplication	AKAP13 MIR7706
esv3637111	Chr.15:85291627 - 85464874 on Build GRCh38	Gain	AKAP13 MIR7706
nsv570296	Chr.15:85237085 - 85383609 on Build GRCh38	Gain	AKAP13 MIR7706 GOLGA6L3
dgv323n27	Chr.15:85282336 - 85600273 on Build GRCh38	Gain	AKAP13 MIR7706
dgv2647n100	Chr.15:85268380 - 85470404 on Build GRCh38	Gain	AKAP13 MIR7706
nsv518064	Chr.15:85178426 - 85605928 on Build GRCh38	Gain	LOC101929479 LOC642423 AKAP13 MIR7706 GOLGA6L3
dgv4694n54	Chr.15:85344022 - 85600273 on Build GRCh38	Gain	AKAP13 MIR7706
dgv754e212	Chr.15:85181918 - 85597222 on Build GRCh38	Gain	LOC101929479 LOC642423 AKAP13 MIR7706 GOLGA6L3
nsv570298	Chr.15:85272357 - 85510128 on Build GRCh38	Gain	AKAP13 MIR7706
nsv428311	Chr.15:85107707 - 85486274 on Build GRCh38	Gain	LOC101929479 LOC642423 AKAP13 MIR7706 PDE8A GOLGA6L3

More Information

• Set Membership: Intragenic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein phosphorylation
G-protein coupled receptor signaling pathway
heart development
regulation of cardiac muscle hypertrophy
positive regulation of Rho protein signal transduction
intracellular signal transduction
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of GTPase activity
regulation of protein kinase activity
regulation of small GTPase mediated signal transduction
nuclear export
cardiac muscle cell differentiation
regulation of sarcomere organization
bone development
adrenergic receptor signaling pathway
adrenergic receptor signaling pathway involved in heart process
regulation of glucocorticoid mediated signaling pathway

Function(s)

cAMP-dependent protein kinase activity
signal transducer activity
MAP-kinase scaffold activity
guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
protein binding
Rho GTPase binding
protein complex scaffold
metal ion binding
protein kinase A binding