Hs03185021_cn

• Gene Symbol: PPP1R14B
• Assay Reference Genome Location: Chr.11:64244951 on build GRCh38
• Cytoband: 11q13.1

Target Gene Details

• Entrez Gene ID: 26472
• Gene Name: protein phosphatase 1 regulatory inhibitor subunit 14B
• Gene Aliases: PHI-1, PLCB3N, PNG, SOM172
• Location: Chr.11:64244479-64246941 on Build GRCh38
• Assay Gene Location: Overlaps Intron 2 - Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP1R14B	NM_138689.2			NP_619634.1
	AF318364.1			AAL55871.1
	BC014522.2			AAH14522.3
	BC094817.1			AAH94817.1
	BF155230.1
	BT009914.1			AAP88916.1
	X91195.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1159904	Chr.11:64150129 - 64279169 on Build GRCh38	Deletion	PLCB3 DNAJC4 STIP1 PPP1R14B FKBP2 NUDT22 LOC105369340 VEGFB MACROD1 FERMT3 BAD GPR137 TRPT1
nsv951010	Chr.11:63942829 - 64352128 on Build GRCh38	Deletion	PLCB3 STIP1 KCNK4 LOC105369340 VEGFB MACROD1 FERMT3 OTUB1 GPR137 FLRT1 KCNK4-TEX40 DNAJC4 PPP1R14B COX8A FKBP2 PRDX5 ESRRA MIR7155 NUDT22 TRMT112 BAD TEX40 CCDC88B NAA40 TRPT1
dgv1963n54	Chr.11:64174262 - 64329761 on Build GRCh38	Loss	KCNK4-TEX40 PLCB3 DNAJC4 STIP1 PPP1R14B FKBP2 PRDX5 KCNK4 ESRRA NUDT22 LOC105369340 VEGFB FERMT3 TRMT112 BAD TEX40 GPR137 TRPT1
nsv555187	Chr.11:64185649 - 64260416 on Build GRCh38	Loss	PLCB3 DNAJC4 STIP1 PPP1R14B FKBP2 NUDT22 LOC105369340 VEGFB FERMT3 TRPT1
nsv555184	Chr.11:64156974 - 64275525 on Build GRCh38	Loss	PLCB3 DNAJC4 STIP1 PPP1R14B FKBP2 NUDT22 LOC105369340 VEGFB MACROD1 FERMT3 BAD GPR137 TRPT1
nsv832186	Chr.11:64204788 - 64402587 on Build GRCh38	Loss	MIR1237 KCNK4-TEX40 PLCB3 DNAJC4 PPP1R14B FKBP2 PRDX5 KCNK4 ESRRA MIR7155 NUDT22 LOC105369340 VEGFB FERMT3 TRMT112 BAD TEX40 CCDC88B GPR137 RPS6KA4 TRPT1
esv24861	Chr.11:64233793 - 64250642 on Build GRCh38	Gain	DNAJC4 PPP1R14B FKBP2 LOC105369340 VEGFB
nsv983032	Chr.11:64243929 - 64247666 on Build GRCh38	Duplication	PPP1R14B FKBP2 LOC105369340
nsv469961	Chr.11:64055468 - 64318495 on Build GRCh38	Loss	KCNK4-TEX40 PLCB3 DNAJC4 STIP1 PPP1R14B FKBP2 PRDX5 KCNK4 ESRRA NUDT22 LOC105369340 VEGFB MACROD1 FERMT3 TRMT112 BAD TEX40 GPR137 FLRT1 TRPT1

More Information

Additional Information:

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation, Validated

Panther Classification:

Molecular Function -

phosphatase modulator

Gene Ontology Categories:

Process(es)

regulation of protein dephosphorylation
regulation of phosphorylation
negative regulation of catalytic activity
innate immune response

Function(s)

protein serine/threonine phosphatase inhibitor activity