Hs03191961_cn

• Gene Symbol: PPP1R14B
• Assay Reference Genome Location: Chr.11:64244465 on build GRCh38
• Cytoband: 11q13.1

Target Gene Details

• Entrez Gene ID: 26472
• Gene Name: protein phosphatase 1 regulatory inhibitor subunit 14B
• Gene Aliases: PHI-1, PLCB3N, PNG, SOM172
• Location: Chr.11:64244479-64246941 on Build GRCh38
• Assay Gene Location: Overlaps - Exon 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PPP1R14B	NM_138689.2			NP_619634.1
	BC014522.2			AAH14522.3
	BC094817.1			AAH94817.1
	X91195.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv1159904	Chr.11:64150129 - 64279169 on Build GRCh38	Deletion	GPR137 TRPT1 FKBP2 PPP1R14B LOC105369340 MACROD1 DNAJC4 BAD STIP1 PLCB3 NUDT22 VEGFB FERMT3
nsv951010	Chr.11:63942829 - 64352128 on Build GRCh38	Deletion	KCNK4 GPR137 FKBP2 PPP1R14B MACROD1 BAD COX8A FLRT1 PLCB3 TRMT112 NUDT22 PRDX5 OTUB1 TRPT1 LOC105369340 DNAJC4 TEX40 ESRRA CCDC88B STIP1 MIR7155 VEGFB NAA40 FERMT3 KCNK4-TEX40
dgv1963n54	Chr.11:64174262 - 64329761 on Build GRCh38	Loss	KCNK4 GPR137 TRPT1 FKBP2 PPP1R14B LOC105369340 DNAJC4 BAD TEX40 ESRRA STIP1 PLCB3 TRMT112 NUDT22 PRDX5 VEGFB FERMT3 KCNK4-TEX40
nsv555187	Chr.11:64185649 - 64260416 on Build GRCh38	Loss	TRPT1 STIP1 PLCB3 FKBP2 PPP1R14B LOC105369340 NUDT22 DNAJC4 VEGFB FERMT3
nsv555184	Chr.11:64156974 - 64275525 on Build GRCh38	Loss	GPR137 TRPT1 FKBP2 PPP1R14B LOC105369340 MACROD1 DNAJC4 BAD STIP1 PLCB3 NUDT22 VEGFB FERMT3
nsv832186	Chr.11:64204788 - 64402587 on Build GRCh38	Loss	KCNK4 GPR137 TRPT1 FKBP2 PPP1R14B LOC105369340 MIR1237 DNAJC4 BAD TEX40 ESRRA CCDC88B PLCB3 RPS6KA4 MIR7155 TRMT112 NUDT22 PRDX5 VEGFB FERMT3 KCNK4-TEX40
esv24861	Chr.11:64233793 - 64250642 on Build GRCh38	Gain	FKBP2 PPP1R14B LOC105369340 DNAJC4 VEGFB
nsv983032	Chr.11:64243929 - 64247666 on Build GRCh38	Duplication	FKBP2 PPP1R14B LOC105369340
nsv469961	Chr.11:64055468 - 64318495 on Build GRCh38	Loss	KCNK4 GPR137 TRPT1 FKBP2 PPP1R14B LOC105369340 MACROD1 DNAJC4 BAD TEX40 FLRT1 ESRRA STIP1 PLCB3 TRMT112 NUDT22 PRDX5 VEGFB FERMT3 KCNK4-TEX40

More Information

Additional Information:

• Set Membership: Intragenic, Non-exonic, DGV Variation, Validated

Panther Classification:

Molecular Function -

phosphatase modulator

Gene Ontology Categories:

Process(es)

regulation of protein dephosphorylation
regulation of phosphorylation
negative regulation of catalytic activity
innate immune response

Function(s)

protein serine/threonine phosphatase inhibitor activity