Hs03388900_cn

• Gene Symbol: PTPN18
• Assay Reference Genome Location: Chr.2:130356651 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 26469
• Gene Name: protein tyrosine phosphatase, non-receptor type 18
• Gene Aliases: BDP1, PTP-HSCF
• Location: Chr.2:130356007-130375409 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTPN18	NM_001142370.1			NP_001135842.1
	NM_014369.3			NP_055184.2
	XM_006712416.3			XP_006712479.1
	XM_006712417.1			XP_006712480.1
	XM_017003798.1			XP_016859287.1
	AK303804.1
	BC024280.1			AAH24280.1
	BC041562.1			AAH41562.1
	BC052800.1			AAH52800.1
	BI261717.1
	DN995571.1
	X79568.1			CAA56105.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv998333	Chr.2:130059754 - 130454126 on Build GRCh38	Gain+Loss	POTEF NOC2LP1 MZT2B TUBA3E FAR2P2 CCDC115 PTPN18 SMPD4 IMP4 MED15P9 CCDC74B CYP4F62P
esv2760631	Chr.2:130005319 - 130400286 on Build GRCh38	Gain+Loss	FAR2P1 POTEF NOC2LP1 MZT2B TUBA3E CCDC115 PTPN18 SMPD4 IMP4 MED15P9 CCDC74B
nsv583133	Chr.2:130281566 - 130390535 on Build GRCh38	Loss	CCDC115 PTPN18 IMP4
dgv7079n54	Chr.2:130181715 - 130391244 on Build GRCh38	Loss	NOC2LP1 MZT2B TUBA3E CCDC115 PTPN18 SMPD4 IMP4
esv3584065	Chr.2:130046530 - 130400286 on Build GRCh38	Loss	FAR2P1 POTEF NOC2LP1 MZT2B TUBA3E CCDC115 PTPN18 SMPD4 IMP4 MED15P9 CCDC74B
nsv583113	Chr.2:130132813 - 130369588 on Build GRCh38	Gain	NOC2LP1 MZT2B TUBA3E CCDC115 PTPN18 SMPD4 IMP4 MED15P9 CCDC74B
nsv520559	Chr.2:130133334 - 130390535 on Build GRCh38	Gain+Loss	NOC2LP1 MZT2B TUBA3E CCDC115 PTPN18 SMPD4 IMP4 MED15P9 CCDC74B
nsv1005664	Chr.2:130159287 - 130649604 on Build GRCh38	Loss	CFC1 NOC2LP1 MZT2B CCDC115 PTPN18 SMPD4 IMP4 CYP4F62P LOC107985778 CFC1B TISP43 LOC646743 TUBA3E FAR2P2 POTEJ POTEI
esv2763387	Chr.2:130026123 - 130400286 on Build GRCh38	Loss	FAR2P1 POTEF NOC2LP1 MZT2B TUBA3E CCDC115 PTPN18 SMPD4 IMP4 MED15P9 CCDC74B
dgv7080n54	Chr.2:130185940 - 130390535 on Build GRCh38	Gain	NOC2LP1 MZT2B TUBA3E CCDC115 PTPN18 IMP4
nsv459274	Chr.2:128746961 - 130390535 on Build GRCh38	Loss	FAR2P1 LOC101927924 POTEF NOC2LP1 RAB6C MZT2B CCDC115 PTPN18 SMPD4 IMP4 MED15P9 CCDC74B LOC101927881 RAB6C-AS1 TUBA3E LOC151121 LOC389033
dgv7083n54	Chr.2:130236250 - 130440530 on Build GRCh38	Loss	FAR2P2 CCDC115 PTPN18 IMP4 CYP4F62P
esv3592451	Chr.2:130282861 - 130401532 on Build GRCh38	Gain	CCDC115 PTPN18 IMP4
nsv583132	Chr.2:130255764 - 130390535 on Build GRCh38	Gain	CCDC115 PTPN18 IMP4
esv2751826	Chr.2:129606158 - 130385563 on Build GRCh38	Gain	FAR2P1 LOC101927924 POTEF NOC2LP1 RAB6C MZT2B CCDC115 PTPN18 SMPD4 IMP4 MED15P9 CCDC74B RAB6C-AS1 TUBA3E LOC389033
nsv1001073	Chr.2:130290533 - 130400286 on Build GRCh38	Gain	CCDC115 PTPN18 IMP4
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	FAR2P1 POTEF NOC2LP1 MIR4784 CCDC115 AMER3 C2orf27B C2orf27A GPR39 ARHGEF4 ZNF806 FAR2P2 LOC100507460 POTEE MIR663B RAB6C MZT2B PTPN18 IMP4 LOC107985778 LINC01087 CCDC74A CFC1B RAB6C-AS1 LOC440910 PLEKHB2 NOC2LP2 FAM168B POTEI CYP4F30P CFC1 LOC101927924 LINC01120 SMPD4 MZT2A CCDC74B LOC150776 TISP43 LOC646743 TUBA3E FAM201B ANKRD30BL WTH3DI MED15P9 CYP4F62P TUBA3D GPR148 POTEKP POTEJ LOC389033
esv3893326	Chr.2:130080351 - 130492798 on Build GRCh38	Gain	POTEF NOC2LP1 MZT2B CCDC115 PTPN18 SMPD4 IMP4 MED15P9 CCDC74B CYP4F62P TUBA3E FAR2P2 POTEI
dgv4073n100	Chr.2:130091652 - 130400286 on Build GRCh38	Gain	POTEF NOC2LP1 MZT2B TUBA3E CCDC115 PTPN18 SMPD4 IMP4 MED15P9 CCDC74B
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	CFC1 FAR2P1 LOC101927924 POTEF NOC2LP1 CCDC115 AMER3 SMPD4 CCDC74B ARHGEF4 TISP43 LOC646743 TUBA3E FAR2P2 RAB6C MZT2B PTPN18 IMP4 MED15P9 CYP4F62P LOC107985778 CFC1B RAB6C-AS1 GPR148 POTEJ LOC389033 POTEI CYP4F30P

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein dephosphorylation
peptidyl-tyrosine dephosphorylation

Function(s)

non-membrane spanning protein tyrosine phosphatase activity
protein binding