Hs03411373_cn

• Gene Symbol: CD8A
• Assay Reference Genome Location: Chr.2:86796554 on build GRCh38
• Cytoband: 2p11.2

Target Gene Details

• Entrez Gene ID: 925
• Gene Name: CD8a molecule
• Gene Aliases: CD8, Leu2, MAL, p32
• Location: Chr.2:86784605-86808396 on Build GRCh38
• Assay Gene Location: Within Intron 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CD8A	NM_001145873.1			NP_001139345.1
	AK124156.1			BAC85789.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv10063	Chr.2:86713865 - 86857237 on Build GRCh38	Gain	CD8A CD8B RNF103-CHMP3 RMND5A
dgv714e214	Chr.2:86745573 - 86951144 on Build GRCh38	Gain	ANAPC1P1 RGPD1 CD8A CD8B RMND5A
esv25494	Chr.2:86745091 - 86946998 on Build GRCh38	Gain	ANAPC1P1 RGPD1 CD8A CD8B RMND5A
nsv458585	Chr.2:86747195 - 86881088 on Build GRCh38	Gain	ANAPC1P1 CD8A CD8B RMND5A
nsv997982	Chr.2:86745711 - 86878741 on Build GRCh38	Gain	ANAPC1P1 CD8A CD8B RMND5A
esv3591559	Chr.2:86764344 - 86832450 on Build GRCh38	Gain	CD8A CD8B RMND5A
dgv3886n100	Chr.2:86721712 - 86945592 on Build GRCh38	Gain	ANAPC1P1 RGPD1 CD8A CD8B RMND5A

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

T cell mediated immunity
immune response
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
antigen processing and presentation
T cell activation
cytotoxic T cell differentiation
regulation of immune response
positive regulation of calcium-mediated signaling
defense response to virus

Function(s)

protein binding
coreceptor activity
protein kinase binding
MHC class I protein binding
protein homodimerization activity