Hs03429653_cn

• Gene Symbol: PTPN18
• Assay Reference Genome Location: Chr.2:130357341 on build GRCh38
• Cytoband: 2q21.1

Target Gene Details

• Entrez Gene ID: 26469
• Gene Name: protein tyrosine phosphatase, non-receptor type 18
• Gene Aliases: BDP1, PTP-HSCF
• Location: Chr.2:130356007-130375409 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PTPN18	NM_001142370.1			NP_001135842.1
	NM_014369.3			NP_055184.2
	XM_006712416.3			XP_006712479.1
	XM_006712417.1			XP_006712480.1
	XM_017003798.1			XP_016859287.1
	AK303804.1
	BC024280.1			AAH24280.1
	BC041562.1			AAH41562.1
	BC052800.1			AAH52800.1
	BI261717.1
	DN995571.1
	X79568.1			CAA56105.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv998333	Chr.2:130059754 - 130454126 on Build GRCh38	Gain+Loss	PTPN18 MZT2B NOC2LP1 SMPD4 CCDC74B POTEF TUBA3E CCDC115 MED15P9 FAR2P2 IMP4 CYP4F62P
esv2760631	Chr.2:130005319 - 130400286 on Build GRCh38	Gain+Loss	PTPN18 MZT2B NOC2LP1 SMPD4 CCDC74B POTEF TUBA3E CCDC115 MED15P9 FAR2P1 IMP4
nsv583133	Chr.2:130281566 - 130390535 on Build GRCh38	Loss	PTPN18 CCDC115 IMP4
dgv7079n54	Chr.2:130181715 - 130391244 on Build GRCh38	Loss	PTPN18 MZT2B NOC2LP1 SMPD4 TUBA3E CCDC115 IMP4
esv3584065	Chr.2:130046530 - 130400286 on Build GRCh38	Loss	PTPN18 MZT2B NOC2LP1 SMPD4 CCDC74B POTEF TUBA3E CCDC115 MED15P9 FAR2P1 IMP4
nsv583113	Chr.2:130132813 - 130369588 on Build GRCh38	Gain	PTPN18 MZT2B NOC2LP1 SMPD4 CCDC74B TUBA3E CCDC115 MED15P9 IMP4
nsv520559	Chr.2:130133334 - 130390535 on Build GRCh38	Gain+Loss	PTPN18 MZT2B NOC2LP1 SMPD4 CCDC74B TUBA3E CCDC115 MED15P9 IMP4
nsv1005664	Chr.2:130159287 - 130649604 on Build GRCh38	Loss	LOC107985778 LOC646743 POTEJ NOC2LP1 SMPD4 TISP43 TUBA3E POTEI IMP4 CFC1 PTPN18 MZT2B CCDC115 CFC1B FAR2P2 CYP4F62P
esv2763387	Chr.2:130026123 - 130400286 on Build GRCh38	Loss	PTPN18 MZT2B NOC2LP1 SMPD4 CCDC74B POTEF TUBA3E CCDC115 MED15P9 FAR2P1 IMP4
dgv7080n54	Chr.2:130185940 - 130390535 on Build GRCh38	Gain	PTPN18 MZT2B NOC2LP1 TUBA3E CCDC115 IMP4
nsv459274	Chr.2:128746961 - 130390535 on Build GRCh38	Loss	NOC2LP1 RAB6C-AS1 SMPD4 TUBA3E MED15P9 FAR2P1 IMP4 PTPN18 MZT2B RAB6C LOC151121 CCDC74B POTEF LOC101927881 LOC389033 CCDC115 LOC101927924
dgv7083n54	Chr.2:130236250 - 130440530 on Build GRCh38	Loss	PTPN18 CCDC115 FAR2P2 IMP4 CYP4F62P
esv3592451	Chr.2:130282861 - 130401532 on Build GRCh38	Gain	PTPN18 CCDC115 IMP4
nsv583132	Chr.2:130255764 - 130390535 on Build GRCh38	Gain	PTPN18 CCDC115 IMP4
esv2751826	Chr.2:129606158 - 130385563 on Build GRCh38	Gain	NOC2LP1 RAB6C-AS1 SMPD4 TUBA3E MED15P9 FAR2P1 IMP4 PTPN18 MZT2B RAB6C CCDC74B POTEF LOC389033 CCDC115 LOC101927924
nsv1001073	Chr.2:130290533 - 130400286 on Build GRCh38	Gain	PTPN18 CCDC115 IMP4
esv2759092	Chr.2:129589265 - 132440430 on Build GRCh38	Gain+Loss	LOC107985778 POTEJ C2orf27B LOC100507460 MIR4784 CCDC74B POTEF POTEKP CFC1B MIR663B AMER3 GPR148 CYP4F30P SMPD4 TUBA3E POTEI MED15P9 LINC01087 GPR39 MZT2B RAB6C LOC440910 ARHGEF4 MZT2A FAR2P1 PLEKHB2 IMP4 CFC1 PTPN18 NOC2LP2 C2orf27A CCDC115 LOC101927924 CYP4F62P ANKRD30BL LOC646743 NOC2LP1 RAB6C-AS1 WTH3DI ZNF806 TISP43 TUBA3D LINC01120 CCDC74A FAM201B LOC150776 POTEE LOC389033 FAR2P2 FAM168B
esv3893326	Chr.2:130080351 - 130492798 on Build GRCh38	Gain	NOC2LP1 SMPD4 TUBA3E POTEI MED15P9 IMP4 PTPN18 MZT2B CCDC74B POTEF CCDC115 FAR2P2 CYP4F62P
dgv4073n100	Chr.2:130091652 - 130400286 on Build GRCh38	Gain	PTPN18 MZT2B NOC2LP1 SMPD4 CCDC74B POTEF TUBA3E CCDC115 MED15P9 IMP4
nsv428403	Chr.2:129818076 - 130882067 on Build GRCh38	Loss	LOC107985778 POTEJ FAR2P1 IMP4 CFC1 PTPN18 CCDC74B POTEF CCDC115 CFC1B AMER3 LOC101927924 CYP4F62P GPR148 CYP4F30P LOC646743 NOC2LP1 RAB6C-AS1 SMPD4 TISP43 TUBA3E POTEI MED15P9 MZT2B RAB6C ARHGEF4 LOC389033 FAR2P2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

protein dephosphorylation
peptidyl-tyrosine dephosphorylation

Function(s)

non-membrane spanning protein tyrosine phosphatase activity
protein binding