Hs03438100_cn

• Gene Symbol: SPC25
• Assay Reference Genome Location: Chr.2:168872852 on build GRCh38
• Cytoband: 2q24.3

Target Gene Details

• Entrez Gene ID: 57405
• Gene Name: SPC25, NDC80 kinetochore complex component
• Gene Aliases: AD024, SPBC25, hSpc25
• Location: Chr.2:168865045-168890443 on Build GRCh38
• Assay Gene Location: Within Intron 6

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SPC25	NM_020675.3			NP_065726.1
	XM_011511516.2			XP_011509818.1
	AF225416.1			AAG09718.1
	AK291093.1
	AY456388.1			AAR88652.1
	BC022255.1			AAH22255.1
	CR457197.1			CAG33478.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv227	Chr.2:168864813 - 168882855 on Build GRCh38	Insertion	SPC25 NOSTRIN
nsv583599	Chr.2:168807717 - 169046586 on Build GRCh38	Gain	G6PC2 ABCB11 SPC25 NOSTRIN
nsv3023	Chr.2:168859032 - 168882855 on Build GRCh38	Insertion	SPC25 NOSTRIN

More Information

Additional Information:

For this assay, SNP(s) [rs112075308] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

mitotic spindle organization
chromosome segregation
sister chromatid cohesion
mitotic nuclear division
cell division

Function(s)

protein binding