Hs03448331_cn

• Gene Symbol: NPPC
• Assay Reference Genome Location: Chr.2:231922613 on build GRCh38
• Cytoband: 2q37.1

Target Gene Details

• Entrez Gene ID: 4880
• Gene Name: natriuretic peptide C
• Gene Aliases: CNP, CNP2
• Location: Chr.2:231922094-231926403 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
NPPC	NM_024409.3			NP_077720.1
	XM_011511245.2	3	2392	XP_011509547.1
	DR003533.1
	JF420840.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2759117	Chr.2:231672114 - 232141148 on Build GRCh38	Gain+Loss	COPS7B PDE6D MIR1244-1 PTMA NPPC MIR1471 DIS3L2
nsv508892	Chr.2:231889469 - 231940618 on Build GRCh38	Insertion	NPPC MIR1471

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

peptide hormone

Gene Ontology Categories:

Process(es)

ossification
response to hypoxia
growth plate cartilage chondrocyte differentiation
growth plate cartilage chondrocyte proliferation
cGMP biosynthetic process
receptor guanylyl cyclase signaling pathway
negative regulation of cell proliferation
post-embryonic development
regulation of cAMP metabolic process
regulation of cGMP metabolic process
positive regulation of cGMP biosynthetic process
regulation of multicellular organism growth
response to drug
single organism reproductive process
response to ethanol
positive regulation of osteoblast differentiation
positive regulation of vasodilation
regulation of smooth muscle cell proliferation
negative regulation of DNA metabolic process
negative regulation of meiotic cell cycle
negative regulation of oocyte maturation
regulation of cardiac conduction

Function(s)

receptor binding
hormone activity
protein homodimerization activity
peptide hormone receptor binding