Hs03452510_cn

• Gene Symbol: CLDN18
• Assay Reference Genome Location: Chr.3:138013720 on build GRCh38
• Cytoband: 3q22.3

Target Gene Details

• Entrez Gene ID: 51208
• Gene Name: claudin 18
• Gene Aliases: SFTA5, SFTPJ
• Location: Chr.3:137998816-138033652 on Build GRCh38
• Assay Gene Location: Within Intron 2

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
CLDN18	NM_001002026.2			NP_001002026.1
	NM_016369.3			NP_057453.1
	AF221069.1			AAF26448.1
	AF349452.1			AAL15637.1
	AK098474.1
	AK298103.1
	AY358479.1			AAQ88843.1
	BC142708.1
	BC146668.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv428422	Chr.3:137344347 - 138686784 on Build GRCh38	Gain+Loss	A4GNT NME9 DBR1 ARMC8 FAIM CEP70 MRAS CLDN18 ESYT3 PIK3CB SOX14 LINC01210 DZIP1L
nsv591852	Chr.3:137964915 - 138022297 on Build GRCh38	Loss	CLDN18
esv2751978	Chr.3:137996460 - 138171908 on Build GRCh38	Loss	A4GNT DBR1 DZIP1L CLDN18
esv2759180	Chr.3:137892947 - 138214993 on Build GRCh38	Loss	A4GNT DBR1 ARMC8 DZIP1L CLDN18

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

tight junction

Gene Ontology Categories:

Process(es)

calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
negative regulation of bone resorption
digestive tract development
TNFSF11-mediated signaling pathway
negative regulation of protein localization to nucleus
negative regulation of osteoclast development

Function(s)

structural molecule activity
identical protein binding