Hs03546527_cn

• Gene Symbol: EXOC3
• Assay Reference Genome Location: Chr.5:444395 on build GRCh38
• Cytoband: 5p15.33

Target Gene Details

• Entrez Gene ID: 11336
• Gene Name: exocyst complex component 3
• Gene Aliases: SEC6, SEC6L1, Sec6p
• Location: Chr.5:443184-471938 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXOC3	NM_007277.4			NP_009208.2
	XM_011513948.2			XP_011512250.1
	XM_011513951.2			XP_011512253.1
	XM_017009000.1			XP_016864489.1
	XM_017009001.1			XP_016864490.1
	XM_017009002.1			XP_016864491.1
	XM_017009003.1			XP_016864492.1
	XM_017009004.1			XP_016864493.1
	XM_017009005.1			XP_016864494.1
	XM_017009006.1			XP_016864495.1
	AL545132.3
	GU727644.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3894107	Chr.5:81322 - 801057 on Build GRCh38	Gain	AHRR SLC9A3 PP7080 HRAT5 MIR4456 LOC101929895 LOC100996325 TPPP LOC100288152 LRRC14B ZDHHC11B PLEKHG4B CEP72 SDHA EXOC3 CCDC127 PDCD6 ZDHHC11 EXOC3-AS1
nsv830183	Chr.5:349237 - 502409 on Build GRCh38	Gain+Loss	AHRR LOC100288152 SLC9A3 PP7080 EXOC3 EXOC3-AS1
nsv1032584	Chr.5:375290 - 809679 on Build GRCh38	Gain	AHRR SLC9A3 PP7080 MIR4456 LOC101929895 LOC100996325 TPPP LOC100288152 ZDHHC11B CEP72 EXOC3 ZDHHC11 EXOC3-AS1
nsv596626	Chr.5:429874 - 598109 on Build GRCh38	Gain	AHRR LOC100288152 SLC9A3 PP7080 MIR4456 EXOC3 EXOC3-AS1
nsv1030767	Chr.5:154674 - 457840 on Build GRCh38	Gain	AHRR LRRC14B PLEKHG4B HRAT5 SDHA EXOC3 CCDC127 PDCD6 EXOC3-AS1
nsv461890	Chr.5:438449 - 539195 on Build GRCh38	Gain	LOC100288152 SLC9A3 PP7080 MIR4456 EXOC3 EXOC3-AS1
esv2759315	Chr.5:17263 - 595840 on Build GRCh38	Loss	AHRR SLC9A3 PP7080 HRAT5 MIR4456 LOC100288152 LRRC14B PLEKHG4B SDHA EXOC3 CCDC127 PDCD6 EXOC3-AS1
nsv1032824	Chr.5:335214 - 449516 on Build GRCh38	Gain	AHRR EXOC3 EXOC3-AS1
esv3603744	Chr.5:359572 - 478120 on Build GRCh38	Gain	AHRR LOC100288152 SLC9A3 PP7080 EXOC3 EXOC3-AS1
nsv4673	Chr.5:414170 - 449449 on Build GRCh38	Insertion	AHRR EXOC3 EXOC3-AS1
esv2752071	Chr.5:378298 - 699075 on Build GRCh38	Gain	LOC100996325 AHRR TPPP LOC100288152 SLC9A3 PP7080 CEP72 MIR4456 EXOC3 LOC101929895 EXOC3-AS1
nsv1019215	Chr.5:346521 - 661696 on Build GRCh38	Gain	LOC100996325 AHRR TPPP LOC100288152 SLC9A3 PP7080 CEP72 MIR4456 EXOC3 EXOC3-AS1
nsv1027279	Chr.5:337575 - 531110 on Build GRCh38	Gain	AHRR LOC100288152 SLC9A3 PP7080 EXOC3 EXOC3-AS1
nsv830184	Chr.5:378153 - 451752 on Build GRCh38	Gain	AHRR EXOC3 EXOC3-AS1
esv3603745	Chr.5:376684 - 458243 on Build GRCh38	Gain	AHRR EXOC3 EXOC3-AS1

More Information

Additional Information:

For this assay, SNP(s) [rs72717430] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane traffic protein

Gene Ontology Categories:

Process(es)

exocytosis
protein transport
exocyst localization
cell-cell adhesion

Function(s)

SNARE binding
protein binding
cadherin binding involved in cell-cell adhesion