Hs03546527_cn

• Gene Symbol: EXOC3
• Assay Reference Genome Location: Chr.5:444395 on build GRCh38
• Cytoband: 5p15.33

Target Gene Details

• Entrez Gene ID: 11336
• Gene Name: exocyst complex component 3
• Gene Aliases: SEC6, SEC6L1, Sec6p
• Location: Chr.5:443184-471938 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
EXOC3	NM_007277.4			NP_009208.2
	XM_011513948.2			XP_011512250.1
	XM_011513951.2			XP_011512253.1
	XM_017009000.1			XP_016864489.1
	XM_017009001.1			XP_016864490.1
	XM_017009002.1			XP_016864491.1
	XM_017009003.1			XP_016864492.1
	XM_017009004.1			XP_016864493.1
	XM_017009005.1			XP_016864494.1
	XM_017009006.1			XP_016864495.1
	AL545132.3
	GU727644.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv3894107	Chr.5:81322 - 801057 on Build GRCh38	Gain	LOC100288152 PP7080 CEP72 LRRC14B SDHA PLEKHG4B PDCD6 LOC101929895 CCDC127 MIR4456 AHRR EXOC3 ZDHHC11 LOC100996325 ZDHHC11B SLC9A3 TPPP HRAT5 EXOC3-AS1
nsv830183	Chr.5:349237 - 502409 on Build GRCh38	Gain+Loss	LOC100288152 PP7080 SLC9A3 AHRR EXOC3-AS1 EXOC3
nsv1032584	Chr.5:375290 - 809679 on Build GRCh38	Gain	LOC100288152 PP7080 CEP72 LOC101929895 MIR4456 AHRR EXOC3 ZDHHC11 LOC100996325 ZDHHC11B SLC9A3 TPPP EXOC3-AS1
nsv461889	Chr.5:429874 - 598109 on Build GRCh38	Gain	LOC100288152 PP7080 SLC9A3 MIR4456 AHRR EXOC3-AS1 EXOC3
nsv1030767	Chr.5:154674 - 457840 on Build GRCh38	Gain	LRRC14B SDHA PLEKHG4B PDCD6 CCDC127 AHRR HRAT5 EXOC3-AS1 EXOC3
dgv9479n54	Chr.5:438449 - 567131 on Build GRCh38	Gain	LOC100288152 PP7080 SLC9A3 MIR4456 EXOC3-AS1 EXOC3
esv2759315	Chr.5:17263 - 595840 on Build GRCh38	Loss	LOC100288152 PP7080 LRRC14B SDHA PLEKHG4B PDCD6 CCDC127 MIR4456 AHRR EXOC3 SLC9A3 HRAT5 EXOC3-AS1
nsv1032824	Chr.5:335214 - 449516 on Build GRCh38	Gain	AHRR EXOC3-AS1 EXOC3
esv3603744	Chr.5:359572 - 478120 on Build GRCh38	Gain	LOC100288152 PP7080 SLC9A3 AHRR EXOC3-AS1 EXOC3
nsv4673	Chr.5:414170 - 449449 on Build GRCh38	Insertion	AHRR EXOC3-AS1 EXOC3
nsv1027279	Chr.5:337575 - 531110 on Build GRCh38	Gain	LOC100288152 PP7080 SLC9A3 AHRR EXOC3-AS1 EXOC3
nsv1019215	Chr.5:346521 - 661696 on Build GRCh38	Gain	LOC100288152 LOC100996325 PP7080 CEP72 SLC9A3 MIR4456 AHRR TPPP EXOC3-AS1 EXOC3
esv2752071	Chr.5:378298 - 699075 on Build GRCh38	Gain	LOC100288152 LOC100996325 PP7080 CEP72 SLC9A3 LOC101929895 MIR4456 AHRR TPPP EXOC3-AS1 EXOC3
nsv830184	Chr.5:378153 - 451752 on Build GRCh38	Gain	AHRR EXOC3-AS1 EXOC3
esv3603745	Chr.5:376684 - 458243 on Build GRCh38	Gain	AHRR EXOC3-AS1 EXOC3

More Information

Additional Information:

For this assay, SNP(s) [rs72717430] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

membrane traffic protein

Gene Ontology Categories:

Process(es)

exocytosis
protein transport
exocyst localization
cell-cell adhesion

Function(s)

SNARE binding
protein binding
cadherin binding involved in cell-cell adhesion