Hs03571210_cn

• Gene Symbol: SLF1
• Assay Reference Genome Location: Chr.5:94645766 on build GRCh38
• Cytoband: 5q15

Target Gene Details

• Entrez Gene ID: 84250
• Gene Name: SMC5-SMC6 complex localization factor 1
• Gene Aliases: ANKRD32, BRCTD1, BRCTx
• Location: Chr.5:94613477-94697733 on Build GRCh38
• Assay Gene Location: Within Intron 7

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
SLF1	NM_032290.3			NP_115666.2
	XM_017009978.1			XP_016865467.1
	XM_017009979.1			XP_016865468.1
	XM_017009980.1			XP_016865469.1
	XM_017009981.1			XP_016865470.1
	XM_017009982.1			XP_016865471.1
	AK297452.1
	AK299080.1
	AL050298.1			CAB43397.2
	BC054885.1			AAH54885.2
	BC070332.1			AAH70332.1
	BC107571.1			AAI07572.1
	BU431750.1
	CR936768.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv435825	Chr.5:94642472 - 94648809 on Build GRCh38	Deletion	SLF1
nsv462254	Chr.5:94621232 - 94721120 on Build GRCh38	Loss	SLF1 MCTP1
esv2759354	Chr.5:94429500 - 94706496 on Build GRCh38	Loss	SLF1 MCTP1 KIAA0825

More Information

Additional Information:

For this assay, SNP(s) [rs79372314] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

DNA repair
cellular response to DNA damage stimulus
positive regulation of protein complex assembly
positive regulation of maintenance of mitotic sister chromatid cohesion
protein localization to site of double-strand break
positive regulation of double-strand break repair

Function(s)

protein binding
ubiquitin protein ligase binding
protein complex binding