Hs03624406_cn

• Gene Symbol: YWHAG
• Assay Reference Genome Location: Chr.7:76344904 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 7532
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
• Gene Aliases: 14-3-3GAMMA, PPP1R170
• Location: Chr.7:76326791-76359025 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YWHAG	NM_012479.3			NP_036611.2
	AB024334.1			BAA85184.1
	AF142498.1			AAD48408.1
	AK024230.1
	AK293505.1
	AK295029.1
	BC020963.2			AAH20963.1
	CR541904.1			CAG46702.1
	CR541925.1			CAG46723.1
	DC343104.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422494	Chr.7:76286900 - 76984449 on Build GRCh38	Duplication	YWHAG DTX2P1-UPK3BP1-PMS2P11 SSC4D ZP3 HSPB1 FDPSP2 LOC105375355 DTX2 POMZP3 SPDYE16 SRRM3 LOC100133091
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	SSC4D TRIM73 PMS2P3 POR LOC105375355 MIR4651 SRRM3 LOC100133091 SNORA14A GTF2IP7 ZP3 SPDYE5 PMS2P10 NCF1C STYXL1 POMZP3 GTF2IP1 LOC441259 YWHAG RHBDD2 FDPSP2 STAG3L1 DTX2 HIP1 SPDYE16 LOC541473 HSPB1 CCL24 CCL26 POM121C TMEM120A MDH2 PMS2P2 GTF2IRD2B LOC107986711 NSUN5P1
nsv428174	Chr.7:76305019 - 77220062 on Build GRCh38	Gain	YWHAG FGL2 DTX2P1-UPK3BP1-PMS2P11 SSC4D CCDC146 FDPSP2 LOC105375355 DTX2 SPDYE16 LOC100133091 ZP3 PMS2P9 POMZP3 SPDYE17 SPDYE18
nsv1028665	Chr.7:76336044 - 76445651 on Build GRCh38	Gain	YWHAG SSC4D ZP3
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	SSC4D PMS2P3 POR LOC105375355 MIR4651 SRRM3 LOC100133091 SNORA14A GTF2IP7 ZP3 SPDYE5 STYXL1 POMZP3 YWHAG RHBDD2 FDPSP2 DTX2 HIP1 SPDYE16 HSPB1 CCL24 CCL26 POM121C TMEM120A MDH2 LOC107986711

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
negative regulation of protein kinase activity
protein targeting
regulation of signal transduction
cellular response to insulin stimulus
regulation of neuron differentiation
regulation of synaptic plasticity
membrane organization
negative regulation of protein serine/threonine kinase activity
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

protein kinase C binding
insulin-like growth factor receptor binding
protein binding
protein kinase C inhibitor activity
protein domain specific binding
receptor tyrosine kinase binding
poly(A) RNA binding