Hs03627961_cn

• Gene Symbol: POLR2J
• Assay Reference Genome Location: Chr.7:102473909 on build GRCh38
• Cytoband: 7q22.1

Target Gene Details

• Entrez Gene ID: 5439
• Gene Name: RNA polymerase II subunit J
• Gene Aliases: POLR2J1, RPB11, RPB11A, RPB11m, hRPB14
• Location: Chr.7:102473100-102478999 on Build GRCh38
• Assay Gene Location: Within Exon 3

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
POLR2J	NM_006234.4			NP_006225.1
	XM_005250452.4	3	909	XP_005250509.1
	XM_017012353.1			XP_016867842.1
	AK290515.1
	BC024165.1			AAH24165.1
	BC065711.1			AAH65711.1
	BC139902.1
	BC141830.1
	BM545237.1
	BM791979.1
	L37127.1			AAD05361.1
	X82385.1			CAA57785.1
	X98433.1			CAA67075.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv831083	Chr.7:102340560 - 102655422 on Build GRCh38	Loss	LRWD1 RASA4 MIR5090 PRKRIP1 LOC100630923 UPK3BL SPDYE2B RASA4B POLR2J2 ALKBH4 LOC100289561 SPDYE2 LOC107983993 MIR548O ORAI2 LOC102724229 POLR2J MIR4467 SPDYE6 POLR2J3
nsv471450	Chr.7:102473103 - 102478934 on Build GRCh38	Gain	LRWD1 POLR2J
dgv23n31	Chr.7:102473939 - 102777602 on Build GRCh38	Gain	FAM185A LOC102724229 RASA4 POLR2J UPK3BL SPDYE2B RASA4B FBXL13 POLR2J2 SPDYE2 POLR2J3 LOC107983993
nsv608005	Chr.7:102473640 - 102690366 on Build GRCh38	Gain	LOC102724229 RASA4 POLR2J UPK3BL SPDYE2B RASA4B POLR2J2 SPDYE2 POLR2J3 LOC107983993
dgv11541n54	Chr.7:102473462 - 102646638 on Build GRCh38	Loss	LOC102724229 RASA4 POLR2J UPK3BL RASA4B POLR2J2 SPDYE2 POLR2J3 LOC107983993
nsv8192	Chr.7:102450605 - 102692752 on Build GRCh38	Gain	LRWD1 RASA4 MIR5090 UPK3BL SPDYE2B RASA4B POLR2J2 ALKBH4 SPDYE2 LOC107983993 ORAI2 LOC102724229 POLR2J MIR4467 POLR2J3
esv27624	Chr.7:102472919 - 102691417 on Build GRCh38	Gain+Loss	LOC102724229 LRWD1 RASA4 POLR2J UPK3BL SPDYE2B RASA4B POLR2J2 SPDYE2 POLR2J3 LOC107983993
dgv6538n100	Chr.7:102171110 - 103063688 on Build GRCh38	Gain	MIR5090 PRKRIP1 LOC100630923 UPK3BL SPDYE2B POLR2J2 LOC107983993 MIR548O FAM185A ORAI2 LOC102724229 MIR4467 SPDYE6 POLR2J3 LRWD1 RASA4 RASA4B SH2B2 FBXL13 CUX1 ALKBH4 LOC100289561 SPDYE2 MIR4285 POLR2J NFE4 LRRC17
nsv428182	Chr.7:102257460 - 102735503 on Build GRCh38	Gain	LRWD1 RASA4 MIR5090 PRKRIP1 LOC100630923 UPK3BL SPDYE2B RASA4B SH2B2 FBXL13 POLR2J2 CUX1 ALKBH4 LOC100289561 SPDYE2 LOC107983993 MIR548O ORAI2 LOC102724229 MIR4285 POLR2J MIR4467 SPDYE6 POLR2J3
nsv5879	Chr.7:102450321 - 102747356 on Build GRCh38	Deletion	LRWD1 RASA4 MIR5090 UPK3BL SPDYE2B RASA4B FBXL13 POLR2J2 ALKBH4 SPDYE2 LOC107983993 ORAI2 LOC102724229 POLR2J MIR4467 POLR2J3

More Information

• Set Membership: Intragenic, Exonic, DGV Variation

Panther Classification:

Molecular Function -

DNA-directed RNA polymerase, RNA metabolism protein, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

mRNA splicing, via spliceosome
transcription-coupled nucleotide-excision repair
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
7-methylguanosine mRNA capping
fibroblast growth factor receptor signaling pathway
gene expression
gene silencing by RNA
somatic stem cell population maintenance
snRNA transcription from RNA polymerase II promoter
positive regulation of viral transcription

Function(s)

RNA polymerase II activity
DNA binding
DNA-directed RNA polymerase activity
protein binding
LRR domain binding
protein dimerization activity