Hs03629424_cn

• Gene Symbol: YWHAG
• Assay Reference Genome Location: Chr.7:76340342 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 7532
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
• Gene Aliases: 14-3-3GAMMA, PPP1R170
• Location: Chr.7:76326791-76359025 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YWHAG	NM_012479.3			NP_036611.2
	AB024334.1			BAA85184.1
	AF142498.1			AAD48408.1
	AK024230.1
	AK293505.1
	AK295029.1
	BC020963.2			AAH20963.1
	CR541904.1			CAG46702.1
	CR541925.1			CAG46723.1
	DC343104.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422494	Chr.7:76286900 - 76984449 on Build GRCh38	Duplication	HSPB1 YWHAG LOC105375355 LOC100133091 ZP3 DTX2 SSC4D FDPSP2 POMZP3 SPDYE16 DTX2P1-UPK3BP1-PMS2P11 SRRM3
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	HSPB1 CCL26 GTF2IRD2B LOC100133091 CCL24 LOC441259 SSC4D FDPSP2 SPDYE16 STAG3L1 YWHAG PMS2P3 NCF1C MDH2 LOC107986711 STYXL1 TMEM120A ZP3 DTX2 SNORA14A RHBDD2 TRIM73 PMS2P10 LOC105375355 PMS2P2 SPDYE5 LOC541473 GTF2IP7 HIP1 SRRM3 NSUN5P1 MIR4651 POM121C POMZP3 GTF2IP1 POR
nsv428174	Chr.7:76305019 - 77220062 on Build GRCh38	Gain	LOC105375355 LOC100133091 FGL2 CCDC146 SSC4D FDPSP2 SPDYE18 SPDYE16 YWHAG PMS2P9 ZP3 DTX2 SPDYE17 POMZP3 DTX2P1-UPK3BP1-PMS2P11
nsv1028665	Chr.7:76336044 - 76445651 on Build GRCh38	Gain	YWHAG ZP3 SSC4D
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	HSPB1 CCL26 LOC100133091 CCL24 SSC4D FDPSP2 SPDYE16 YWHAG PMS2P3 MDH2 LOC107986711 STYXL1 TMEM120A ZP3 DTX2 SNORA14A RHBDD2 LOC105375355 SPDYE5 GTF2IP7 HIP1 SRRM3 MIR4651 POM121C POMZP3 POR

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
negative regulation of protein kinase activity
protein targeting
regulation of signal transduction
cellular response to insulin stimulus
regulation of neuron differentiation
regulation of synaptic plasticity
membrane organization
negative regulation of protein serine/threonine kinase activity
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

protein kinase C binding
insulin-like growth factor receptor binding
protein binding
protein kinase C inhibitor activity
protein domain specific binding
receptor tyrosine kinase binding
poly(A) RNA binding