Hs03630604_cn

• Gene Symbol: YWHAG
• Assay Reference Genome Location: Chr.7:76351228 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 7532
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
• Gene Aliases: 14-3-3GAMMA, PPP1R170
• Location: Chr.7:76326791-76359025 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YWHAG	NM_012479.3			NP_036611.2
	AB024334.1			BAA85184.1
	AF142498.1			AAD48408.1
	AK024230.1
	AK293505.1
	AK295029.1
	BC020963.2			AAH20963.1
	CR541904.1			CAG46702.1
	CR541925.1			CAG46723.1
	DC343104.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422494	Chr.7:76286900 - 76984449 on Build GRCh38	Duplication	SRRM3 YWHAG POMZP3 DTX2 LOC100133091 DTX2P1-UPK3BP1-PMS2P11 FDPSP2 SSC4D HSPB1 LOC105375355 ZP3 SPDYE16
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	PMS2P2 CCL26 ZP3 POM121C CCL24 YWHAG FDPSP2 TRIM73 HSPB1 GTF2IRD2B RHBDD2 PMS2P10 NSUN5P1 GTF2IP7 POMZP3 STYXL1 SNORA14A NCF1C MIR4651 HIP1 LOC441259 LOC107986711 TMEM120A GTF2IP1 SSC4D SPDYE5 MDH2 SPDYE16 POR SRRM3 LOC541473 DTX2 LOC100133091 STAG3L1 LOC105375355 PMS2P3
nsv428174	Chr.7:76305019 - 77220062 on Build GRCh38	Gain	POMZP3 PMS2P9 SSC4D ZP3 CCDC146 SPDYE16 YWHAG DTX2 LOC100133091 DTX2P1-UPK3BP1-PMS2P11 SPDYE17 FDPSP2 LOC105375355 SPDYE18 FGL2
nsv1028665	Chr.7:76336044 - 76445651 on Build GRCh38	Gain	YWHAG SSC4D ZP3
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	CCL26 ZP3 POM121C CCL24 YWHAG FDPSP2 HSPB1 RHBDD2 GTF2IP7 POMZP3 STYXL1 SNORA14A MIR4651 HIP1 LOC107986711 TMEM120A SSC4D SPDYE5 MDH2 SPDYE16 POR SRRM3 DTX2 LOC100133091 LOC105375355 PMS2P3

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
negative regulation of protein kinase activity
protein targeting
regulation of signal transduction
cellular response to insulin stimulus
regulation of neuron differentiation
regulation of synaptic plasticity
membrane organization
negative regulation of protein serine/threonine kinase activity
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

protein kinase C binding
insulin-like growth factor receptor binding
protein binding
protein kinase C inhibitor activity
protein domain specific binding
receptor tyrosine kinase binding
poly(A) RNA binding