Hs03631504_cn

• Gene Symbol: LAMTOR4
• Assay Reference Genome Location: Chr.7:100136634 on build GRCh38
• Cytoband: 7q22.1

Target Gene Details

• Entrez Gene ID: 389541
• Gene Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
• Gene Aliases: C7orf59
• Location: Chr.7:100130969-100154212 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
LAMTOR4	XM_017012198.1			XP_016867687.1
	XM_017012199.1			XP_016867688.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv607931	Chr.7:100067194 - 100198523 on Build GRCh38	Loss	COPS6 MIR106B MBLAC1 MCM7 MIR25 STAG3 GPC2 AP4M1 MIR93 GATS MIR4658 LAMTOR4 CNPY4 TAF6 C7orf43 GAL3ST4 ZNF3
nsv469687	Chr.7:99974920 - 100157518 on Build GRCh38	Loss	COPS6 MIR106B MBLAC1 MCM7 MIR25 ZKSCAN1 AZGP1P1 AP4M1 MIR93 AZGP1 MIR4658 LAMTOR4 CNPY4 TAF6 C7orf43 ZSCAN21 ZNF3
esv2734888	Chr.7:99975623 - 101290285 on Build GRCh38	Deletion	FBXO24 ACHE STAG3L5P-PVRIG2P-PILRB MIR25 SRRT POP7 LOC105375429 MOSPD3 AZGP1P1 AP1S1 ACTL6B GNB2 AZGP1 LOC102724094 MIR4658 C7orf43 ZNF3 EPHB4 MBLAC1 PLOD3 GIGYF1 PPP1R35 SPDYE3 ZCWPW1 TSC22D4 AGFG2 MIR93 FIS1 MIR4653 MEPCE ZNHIT1 MUC17 MUC3A PMS2P1 COPS6 PCOLCE-AS1 PVRIG MIR106B MCM7 PCOLCE ZKSCAN1 CLDN15 EPO GPC2 SAP25 TRIP6 GATS LRCH4 TRIM56 VGF MIR6875 SERPINE1 PVRIG2P NYAP1 LAMTOR4 CNPY4 SLC12A9 ZSCAN21 TFR2 MIR6840 UFSP1 PILRA ZAN NAT16 STAG3L5P STAG3 ZASP MOGAT3 AP4M1 PILRB C7orf61 MUC12 TAF6 GAL3ST4

More Information

Additional Information:

For this assay, SNP(s) [rs77639804] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Gene Ontology Categories:

Process(es)

cell cycle arrest
regulation of cell size
macroautophagy
positive regulation of TOR signaling
positive regulation of GTPase activity
protein localization to lysosome
cellular response to amino acid stimulus

Function(s)

guanyl-nucleotide exchange factor activity
protein binding
protein complex scaffold