Hs03634848_cn

• Gene Symbol: YWHAG
• Assay Reference Genome Location: Chr.7:76352368 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 7532
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
• Gene Aliases: 14-3-3GAMMA, PPP1R170
• Location: Chr.7:76326791-76359025 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YWHAG	NM_012479.3			NP_036611.2
	AB024334.1			BAA85184.1
	AF142498.1			AAD48408.1
	AK024230.1
	AK293505.1
	AK295029.1
	BC020963.2			AAH20963.1
	CR541904.1			CAG46702.1
	CR541925.1			CAG46723.1
	DC343104.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422494	Chr.7:76286900 - 76984449 on Build GRCh38	Duplication	ZP3 SSC4D POMZP3 DTX2 SPDYE16 FDPSP2 SRRM3 LOC105375355 HSPB1 YWHAG DTX2P1-UPK3BP1-PMS2P11 LOC100133091
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	LOC541473 SPDYE16 POR TRIM73 CCL24 GTF2IP1 DTX2 NSUN5P1 CCL26 TMEM120A NCF1C LOC441259 LOC100133091 MIR4651 LOC107986711 SSC4D POM121C SRRM3 HIP1 PMS2P10 YWHAG SPDYE5 GTF2IP7 PMS2P3 ZP3 PMS2P2 POMZP3 FDPSP2 STAG3L1 MDH2 GTF2IRD2B SNORA14A LOC105375355 RHBDD2 HSPB1 STYXL1
nsv428174	Chr.7:76305019 - 77220062 on Build GRCh38	Gain	CCDC146 SSC4D SPDYE16 PMS2P9 SPDYE18 YWHAG ZP3 POMZP3 DTX2 FDPSP2 SPDYE17 LOC105375355 FGL2 DTX2P1-UPK3BP1-PMS2P11 LOC100133091
nsv1028665	Chr.7:76336044 - 76445651 on Build GRCh38	Gain	ZP3 SSC4D YWHAG
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	SPDYE16 POR CCL24 DTX2 CCL26 TMEM120A LOC100133091 MIR4651 LOC107986711 SSC4D POM121C SRRM3 HIP1 YWHAG SPDYE5 GTF2IP7 PMS2P3 ZP3 POMZP3 FDPSP2 MDH2 SNORA14A LOC105375355 RHBDD2 HSPB1 STYXL1

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
negative regulation of protein kinase activity
protein targeting
regulation of signal transduction
cellular response to insulin stimulus
regulation of neuron differentiation
regulation of synaptic plasticity
membrane organization
negative regulation of protein serine/threonine kinase activity
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

protein kinase C binding
insulin-like growth factor receptor binding
protein binding
protein kinase C inhibitor activity
protein domain specific binding
receptor tyrosine kinase binding
poly(A) RNA binding