Hs03638331_cn

• Gene Symbol: YWHAG
• Assay Reference Genome Location: Chr.7:76342513 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 7532
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
• Gene Aliases: 14-3-3GAMMA, PPP1R170
• Location: Chr.7:76326791-76359025 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YWHAG	NM_012479.3			NP_036611.2
	AB024334.1			BAA85184.1
	AF142498.1			AAD48408.1
	AK024230.1
	AK293505.1
	AK295029.1
	BC020963.2			AAH20963.1
	CR541904.1			CAG46702.1
	CR541925.1			CAG46723.1
	DC343104.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422494	Chr.7:76286900 - 76984449 on Build GRCh38	Duplication	DTX2P1-UPK3BP1-PMS2P11 DTX2 HSPB1 POMZP3 FDPSP2 LOC100133091 LOC105375355 YWHAG SRRM3 SPDYE16 ZP3 SSC4D
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	MIR4651 TMEM120A STYXL1 NSUN5P1 POR LOC100133091 LOC105375355 CCL26 PMS2P2 LOC541473 SPDYE5 FDPSP2 LOC107986711 ZP3 TRIM73 GTF2IP1 MDH2 POM121C PMS2P10 HIP1 DTX2 PMS2P3 CCL24 POMZP3 YWHAG STAG3L1 SSC4D GTF2IP7 NCF1C SNORA14A HSPB1 SRRM3 LOC441259 SPDYE16 RHBDD2 GTF2IRD2B
nsv428174	Chr.7:76305019 - 77220062 on Build GRCh38	Gain	PMS2P9 DTX2 POMZP3 CCDC146 SPDYE17 LOC100133091 LOC105375355 YWHAG SSC4D DTX2P1-UPK3BP1-PMS2P11 SPDYE18 FDPSP2 SPDYE16 ZP3 FGL2
nsv1028665	Chr.7:76336044 - 76445651 on Build GRCh38	Gain	YWHAG ZP3 SSC4D
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	MIR4651 TMEM120A STYXL1 POR LOC100133091 LOC105375355 CCL26 SPDYE5 FDPSP2 LOC107986711 ZP3 MDH2 POM121C HIP1 DTX2 PMS2P3 CCL24 POMZP3 YWHAG SSC4D GTF2IP7 SNORA14A HSPB1 SRRM3 SPDYE16 RHBDD2

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
negative regulation of protein kinase activity
protein targeting
regulation of signal transduction
cellular response to insulin stimulus
regulation of neuron differentiation
regulation of synaptic plasticity
membrane organization
negative regulation of protein serine/threonine kinase activity
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

protein kinase C binding
insulin-like growth factor receptor binding
protein binding
protein kinase C inhibitor activity
protein domain specific binding
receptor tyrosine kinase binding
poly(A) RNA binding