Hs03641783_cn

• Gene Symbol: YWHAG
• Assay Reference Genome Location: Chr.7:76350284 on build GRCh38
• Cytoband: 7q11.23

Target Gene Details

• Entrez Gene ID: 7532
• Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
• Gene Aliases: 14-3-3GAMMA, PPP1R170
• Location: Chr.7:76326791-76359025 on Build GRCh38
• Assay Gene Location: Within Intron 1

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
YWHAG	NM_012479.3			NP_036611.2
	AB024334.1			BAA85184.1
	AF142498.1			AAD48408.1
	AK024230.1
	AK293505.1
	AK295029.1
	BC020963.2			AAH20963.1
	CR541904.1			CAG46702.1
	CR541925.1			CAG46723.1
	DC343104.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv2422494	Chr.7:76286900 - 76984449 on Build GRCh38	Duplication	POMZP3 SSC4D DTX2P1-UPK3BP1-PMS2P11 LOC105375355 SRRM3 DTX2 LOC100133091 SPDYE16 HSPB1 ZP3 FDPSP2 YWHAG
nsv528969	Chr.7:75074053 - 76920728 on Build GRCh38	Gain	LOC541473 LOC441259 NSUN5P1 PMS2P3 POR TMEM120A CCL24 TRIM73 LOC107986711 SPDYE16 ZP3 MIR4651 GTF2IRD2B NCF1C POMZP3 SSC4D SNORA14A CCL26 MDH2 STYXL1 GTF2IP1 RHBDD2 LOC105375355 SRRM3 DTX2 LOC100133091 POM121C SPDYE5 PMS2P10 GTF2IP7 PMS2P2 HIP1 STAG3L1 HSPB1 FDPSP2 YWHAG
nsv428174	Chr.7:76305019 - 77220062 on Build GRCh38	Gain	DTX2P1-UPK3BP1-PMS2P11 LOC105375355 PMS2P9 DTX2 LOC100133091 SPDYE16 ZP3 FGL2 POMZP3 SSC4D SPDYE17 CCDC146 SPDYE18 FDPSP2 YWHAG
nsv1028665	Chr.7:76336044 - 76445651 on Build GRCh38	Gain	SSC4D ZP3 YWHAG
dgv120n16	Chr.7:75440769 - 76641919 on Build GRCh38	Deletion	PMS2P3 POR TMEM120A CCL24 LOC107986711 SPDYE16 ZP3 MIR4651 POMZP3 SSC4D SNORA14A CCL26 MDH2 STYXL1 RHBDD2 LOC105375355 SRRM3 DTX2 LOC100133091 POM121C SPDYE5 GTF2IP7 HIP1 HSPB1 FDPSP2 YWHAG

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

G2/M transition of mitotic cell cycle
negative regulation of protein kinase activity
protein targeting
regulation of signal transduction
cellular response to insulin stimulus
regulation of neuron differentiation
regulation of synaptic plasticity
membrane organization
negative regulation of protein serine/threonine kinase activity
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

protein kinase C binding
insulin-like growth factor receptor binding
protein binding
protein kinase C inhibitor activity
protein domain specific binding
receptor tyrosine kinase binding
poly(A) RNA binding